First recognized community outbreak of haemorrhagic colitis due to verotoxin-producing<i>Escherichia coli</i>O 157.H7 in the UK

Morgan, Gareth J.; Newman, C; Palmer, Sam; Allen, Julie K.; Shepherd, W E; Rampling, Anita; Warren, R. E.; Gross, R. J.; Scotland, Sylvia M.; Smith, H. R.

doi:10.1017/s0950268800029241

Cited by 104 publications

(55 citation statements)

References 17 publications

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“…Faeces samples from which VT + E. coli 0 157 . H7 was identified or free verocytotoxin was present were submitted at a median of 11 days (range [8][9][10][11][12][13][14][15][16] days) compared with 16 days (range 4-23 days) for other persons (X2 for difference in distribution of groups about the median = 9.3, P < 0 001).…”

Section: Resultsmentioning

confidence: 99%

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A christening party outbreak of haemorrhagic colitis and haemolytic uraemic syndrome associated with Escherichia coli O 157. H7

Salmon

Farrell²,

Hutchison³

et al. 1989

Epidemiol. Infect.

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SUMMARYA point source outbreak of haemorrhagic colitis due to Escherichia coli 0 157. 117 producing verocytotoxin (VT), took place following a christening party in Birmingham in June 1987. Twenty-six people were affected, six were admitted to hospital and one developed haemolytic uraemic syndrome: there were no deaths. VT + E. coli 0 157. H7 was isolated from 13 (57 %) of 23 faecal specimens from affected people and from 3 (90%)) of 33 specimens from asymptomatic people.Free VT was detected in the faeces of one further asymptomatic person. Illness was associated with eating turkey-roll sandwiches (P < 0.00 1) suggesting that cold meats might be an important source of infection.

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Section: Resultsmentioning

confidence: 99%

“…Some cases have developed haemolytic uraemic syndrome (HUS) (3)(4)(5)9). In England and Wales sporadic cases of HUS (10) and HC (8) and one outbreak of HC in East Anglia in 1985 (11) (12,13). We describe the first point source outbreak of HC due to E. coli 0 157.117 in the UK.…”

mentioning

confidence: 98%

A christening party outbreak of haemorrhagic colitis and haemolytic uraemic syndrome associated with Escherichia coli O 157. H7

Salmon

Farrell²,

Hutchison³

et al. 1989

Epidemiol. Infect.

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“…With vegetables and fruit, very often there is no intervention step that will provide elimination of infectious pathogens, if they are present. The nonmeat vehicles implicated in disease caused by EHEC, include cheese (Deschenes et al 1996), milk (Upton and Coia 1994), yoghurt (Morgan et al 1993), lettuce (Ackers et al 1998, raw potatoes (Morgan et al 1988), apple juice , radish sprouts (Watanabe et al 1999), alfalfa sprouts, cooked maize (Isaacson et al 1993) and mayonnaise (Weagant et al 1994). Parsley butter contaminated with verotoxigenic Citrobacter freundii has also been associated with severe gastroenteritis and cases of haemolytic uraemic symdrome (Tschape et al 1995).…”

Section: Vehicles Implicated In Foodborne Diseasementioning

confidence: 99%

Survival of Escherichia coli in foods

McClure

Hall

2000

Journal of Applied Microbiology

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SUMMARY Studies describing the survival of Escherichia coli in foods, more often than not use the O157:H7 serovar as the target organism. Whilst E. coli O157:H7 is undoubtedly the predominant agent of concern for foodborne disease caused by enterohaemorrhagic E. coli (EHEC), a consequence of this concern is the commonly held view that this one serovar is ‘atypical’ in its response to stress conditions and therefore better able to survive adverse environments. Many of the studies published do not make comparisons with other E. coli (either commensal organisms or other pathogenic types) or other members of the Enterobacteriaceae, that would justify this view. Nevertheless, there has been a great deal of valuable data and information generated describing the fate of E. coli O157:H7 in a range of foods stored under various conditions. In many respects, the results of these studies are not surprising considering the survivability of other closely related pathogens, such as Shigella spp. This ability to survive in foods for long periods of time confirms the need for reliable control measures where contamination is possible or likely, e.g. proper handling and thorough cooking of beefburgers. The factors that may influence survival in different foods are described, with the intention of providing an insight in this area of food safety. Key considerations for carrying out survival studies are identified, with particular reference to methodologies used.

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“…Two outbreaks of infection have been reported: possible sources of infection were the handling, though not consumption of unwashed potatoes [22], and sliced turkey roll [23]; neither source was confirmed microbiologically. In May-June 1992 there was a suspicion, though not epidemiologically proven, that 5 cases of VT' E. coli 0157 infection in the Sheffield area, 3 of phage type 2 and 2 of phage type 8, may have been associated with consumption of beef originating from a South Yorkshire abattoir.…”

Section: Characterization Of Isolates Of E Coli 0157 Human Isolatesmentioning

confidence: 99%

Cattle as a possible source of verocytotoxin-producingEscherichia coliO157 infections in man

Chapman¹,

Siddons²,

Wright³

et al. 1993

Epidemiol. Infect.

355

217

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SUMMARYIn May-June 1992 cases of infection with verocytotoxin-producing (VT+) Escherichia coli 0157 in South Yorkshire could have been associated with prior consumption of beef from a local abattoir. During investigation of the abattoir, bovine rectal swabs and samples of meat and surface swabs from beef carcasses were examined for E. coli 0157, isolates of which were tested for toxigenicity, plasmid content and phage type. E. coli 0157 was isolated from 84 (4%) of 2103 bovine rectal swabs; of these 84, 78 (93%) were VT', the most common phage types being 2 and 8, the types implicated in the cluster of human cases. Positive cattle were from diverse sources within England. E. coli 0157 was isolated from 7 (30%) of 23 carcasses of rectal swab-positive cattle and from 2 (8%) of 25 carcasses of rectal swab-negative cattle. The study has shown that cattle may be a reservoir of VT+ E. coli 0157, and that contamination of carcasses during slaughter and processing may be how beef and beef products become contaminated and thereby transmit the organism to man.

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First recognized community outbreak of haemorrhagic colitis due to verotoxin-producingEscherichia coliO 157.H7 in the UK

Cited by 104 publications

References 17 publications

A christening party outbreak of haemorrhagic colitis and haemolytic uraemic syndrome associated with Escherichia coli O 157. H7

A christening party outbreak of haemorrhagic colitis and haemolytic uraemic syndrome associated with Escherichia coli O 157. H7

Survival of Escherichia coli in foods

Cattle as a possible source of verocytotoxin-producingEscherichia coliO157 infections in man

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