First record of resistance to flumethrin in a varroa population from Uruguay

Mitton, Giulia; Quintana, Silvina; Martínez, Pablo Giménez; Mendoza, Yamandú; Ramallo, Gustavo; Brasesco, Constanza; Villalba, Agustina; Eguaras, Martín Javier; Maggi, Matías; Ruffinengo, Sergio

doi:10.1080/00218839.2016.1257238

Cited by 17 publications

(6 citation statements)

References 21 publications

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“…Early treatments against V. destructor are essential and comprise the usage of synthetic pyrethroids, such as Fluvalinate and amidines, such as Amitraz ( 8 , 15 ). A common problem is the quick development of resistance, which also leads to cross-resistances against other pyrethroids ( 8 , 16 , 17 ).…”

Section: Introductionmentioning

confidence: 99%

A Detoxification Enzyme for Apis mellifera Newly Characterized by Recombinant Expression: 10-Formyl Tetrahydrofolate Dehydrogenase

2022

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Honeybees are important managed pollinators that perform important ecological and economic functions. In recent decades, the obligate ectoparasite Varroa destructor severely affected survival of honeybees as it either feeds on hemolymph and fat bodies or acts as a vector for viruses. A common treatment against the varroa mite is formic acid, which has been used for many years by beekeepers. This treatment is known to be effective, but the therapeutic index is very narrow. Many beekeepers report negative effects of formic acid on bees, which include damage to brood, worker bee mortality, and queen loss. Little is yet known about the molecular mechanisms of formic acid detoxification in honeybees. Our previous study shows the upregulation of predicted 10-formyl tetrahydrofolate dehydrogenase (10-FTHFDH) transcripts in honeybees exposed to formic acid. Here, the predicted honeybee-specific 10-FTHFDH is recombinantly expressed, and its hydrolase and dehydrogenase activities are investigated. As a result, the enzyme shows similar dehydrogenase activity in comparison to known 10-FTHFDHs. This study provides further knowledge to better understand the detoxification mechanisms of formic acid in Apis mellifera.

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Section: Introductionmentioning

confidence: 99%

A Detoxification Enzyme for Apis mellifera Newly Characterized by Recombinant Expression: 10-Formyl Tetrahydrofolate Dehydrogenase

2022

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“…Synthetic acaricides such as pyrethroids and organophosphates are regularly applied in an attempt to control mite infestations. However, the misuse of these acaricides over time has led to the emergence of several foci of resistant in mite populations worldwide (Elzen and Westervelt 2002;Maggi et al 2009;Maggi et al 2010;Maggi et al 2011;Mitton et al 2016). In addition, the residues of synthetic acaricides persist in bee products (Maggi et al 2016;Medici et al 2015) used for human consumption, making them toxic, and consequently affecting their commercialization (Bogdanov 2006).…”

Section: Introductionmentioning

confidence: 99%

Valorization of hop leaves for development of eco-friendly bee pesticides

et al. 2020

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The bacterium Paenibacillus larvae and the mite Varroa destructor are two of the most severe biotic stressors affecting honeybees and are responsible for American foulbrood and varroosis respectively. To control these pathogens, beekeepers regularly apply synthetic acaricides or antibiotics to parasitized hives. However, antibiotic and acaricide overuse over time leads to resistance in bacteria strains and mite populations respectively, not to mention the residual contamination of bee products with these chemicals. The development of alternative and effective control methods of bee diseases is therefore crucial. In recent years, natural substances from plant extracts have emerged as the basis of suitable control methods to treat bee colonies parasitized by both P. larvae and V. destructor . Our aim was to evaluate the bioactivity of ethanolic and methanolic hop leaf extract (species: Humulus lupulus L, varieties: Victoria, Spalt, and Cascade) against P. larvae , V. destructor , and A. mellifera . The bactericidal activity against P. larvae was evaluated by the broth microdilution method. Topical administration protocols were used to determine the bioactivity of hop extracts on V. destructor and A. mellifera . Total polyphenols, flavonoids, saponins, and antioxidant capacity were determined for each hop leaf extract tested. The Victoria extract had the highest concentration of phenolic compounds, whereas Cascade and Victoria extracts had higher concentrations of the glycoside saponin. All hop extracts presented low toxicity against A. mellifera bees after 48 h of topical administration (except for Cascade ethanolic extract which reached a maximum of 36% of bee mortality). Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values ranged from 0.69 to 2.75 mg/kg for the Cascade variety, 1.38 to 5.5 mg/kg for the Spalt variety, and 5.5 to 11 mg/kg for the Victoria variety. After 48 h, the acaricidal activity for the ethanolic extract of the Victoria variety reached a value close to 80%, while the methanolic extract of Cascade showed an acaricidal activity close to 70%. The results reported in this study support the potential use of methanolic and ethanolic extracts of hop leaves from Argentina as promising natural alternatives for varroosis and American foulbrood control.Paenibacillus larvae / Varroa destructor / Apis mellifera / natural extracts / Humulus lupulus / chemical composition

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“…Por todo o mundo, desde há muito tempo que são conhecidas as resistências aos acaricidas piretróides, entre os quais a flumetrina, devido à sua utilização em larga escala (Milani, 1995;Rodríguez-Dehaibes et al, 2005;Mitton et al, 2016).…”

Section: Resultsunclassified

Eficácia Do Tratamento Combinado De Amitraz E Flumetrina No Controlo Da Varroose

Hipólito¹,

Coelho²,

Pires³

et al. 2022

Agrárias: Pesquisa E Inovação Nas Ciências Que Alimentam O Mundo VIII

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O conteúdo deste livro está licenciado sob uma Licença de Atribuição Creative Commons Atribuição-Não-Comercial NãoDerivativos 4.0 Internacional (CC BY-NC-ND 4.0). Direitos para esta edição cedidos à Editora Artemis pelos autores. Permitido o download da obra e o compartilhamento, desde que sejam atribuídos créditos aos autores, e sem a possibilidade de alterá-la de nenhuma forma ou utilizá-la para fins comerciais.A responsabilidade pelo conteúdo dos artigos e seus dados, em sua forma, correção e confiabilidade é exclusiva dos autores. A Editora Artemis, em seu compromisso de manter e aperfeiçoar a qualidade e confiabilidade dos trabalhos que publica, conduz a avaliação cega pelos pares de todos manuscritos publicados, com base em critérios de neutralidade e imparcialidade acadêmica.

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First record of resistance to flumethrin in a varroa population from Uruguay

Cited by 17 publications

References 21 publications

A Detoxification Enzyme for Apis mellifera Newly Characterized by Recombinant Expression: 10-Formyl Tetrahydrofolate Dehydrogenase

A Detoxification Enzyme for Apis mellifera Newly Characterized by Recombinant Expression: 10-Formyl Tetrahydrofolate Dehydrogenase

Valorization of hop leaves for development of eco-friendly bee pesticides

Eficácia Do Tratamento Combinado De Amitraz E Flumetrina No Controlo Da Varroose

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