First report of Ochrobactrum anthropi isolated from bloodstream infection in Alexandria, Egypt

ElBaradei, Amira; Ahmed, Nancy; Shawky, Sherine

doi:10.21608/mid.2022.129387.1263

Cited by 1 publication

(2 citation statements)

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“…anthropi was also implicated in severe osteomyelitis as an opportunistic infection in an immunocompromised patient 6 . Most reported cases are from developed countries 7 . We report a case of O .…”

Section: Introductionmentioning

confidence: 94%

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Ochrobactrum anthropi sepsis in a 15‐month‐old child: A case report

Adefila,

Osei,

Lamin

et al. 2024

Clinical Case Reports

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Key Clinical MessageOchrobactrum anthropi (O. anthropi), a rare opportunistic pathogen, caused sepsis in a malnourished 15‐month‐old African child. Early detection and appropriate antibiotics led to full recovery, highlighting the importance of robust surveillance for emerging pathogens in vulnerable populations.AbstractWhile rarely causing infections, O. anthropi, a non‐fermenting, obligately aerobic, flagellated gram‐negative bacillus, demonstrates oxidase positivity and indole negativity. Traditionally, Ochrobactrum spp is considered a low threat due to its environmental abundance and mild virulence. It is, however, a multidrug‐resistant bacteria known for causing opportunistic infections in humans. O. anthropi is typically associated with catheter‐related bloodstream infections. The first documented case was in 1998; most cases have been reported in developed countries. We present a case of O. anthropi sepsis in a malnourished child in sub‐Saharan Africa. We report a case involving a 15‐month‐old African female who presented with symptoms and signs of protein‐energy malnutrition and sepsis. The blood culture revealed O.anthropi. We treated the child with the empirical first‐line antibiotics per the national guidelines, intravenous ampicillin and gentamicin for a week, and the child fully recovered. This report describes a rare case of O. anthropi sepsis with malnutrition in an African female child. O. anthropi is an emerging pathogen causing opportunistic infections in both immunocompetent and immunocompromised patients. We report that early bacterial detection, appropriate antibiotic susceptibility and antimicrobial management based on local antibiogram data may be essential for excellent patient outcomes. Additionally, we recommend more robust surveillance to detect such rare emerging pathogens.

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Section: Introductionmentioning

confidence: 94%

“…6 Most reported cases are from developed countries. 7 We report a case of O. anthropi sepsis in a 15-month-old child at a rural hospital in Central River Region, the Gambia.…”

Section: Introductionmentioning

confidence: 97%