First Report of the Australian Corneal Graft Registry

Williams, Keryn A.; Sawyer, Michael; Alfrich, S. J.; Joseph, Lija; White, Michelle A.; Coster, Douglas J.; Mahmood, Muneera A.

doi:10.1111/j.1442-9071.1987.tb00086.x

Cited by 131 publications

(258 citation statements)

References 15 publications

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“…Hence we have considered complicated aphakic and psuedophakic bullous keratopathy as high risk cases. While the success rate of keratoplasty in favourable eyes is claimed to be 90 to 95% [3], it is significantly less in high-risk cases amounting up to -60-70% [5,8]. In this study also the success rate has been about 73%.…”

Section: Discussionmentioning

confidence: 44%

“…This is expected because in bullous keratopathy, the corneal pathology is due to its poor endothelial status of the cornea and its replacement with a healthy and viable graft with good endothelial cell count prevents recurrence of corneal oedema in the graft. [ [2,5,8,9]. The corrected visual acuity remained stable at twelve weeks and one year follow up visits.…”

Section: Discussionmentioning

confidence: 75%

“…This improvement though impressive i-s by no means complete [3-5J. High risk cases like keratolenticular trauma, paediatric corneal involvement, complicated pseudophakic and aphakic bullous keratopathy associated with significant anterior segment derangement, significantly vascularized cornea, dry eye and chemical injuries have significantly lower success rates after keratoplasty [2,5].…”

Section: Introductionmentioning

confidence: 99%

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Penetrating Keratoplasty in High Risk Cases

Parihar

Rodrigues

Ramchandran

et al. 2001

Medical Journal Armed Forces India

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Penetrating Keratoplasty in high risk cases like paediatric patients, complicated cases of pseudophakic bullous keratopathy, or in patients with highly vascularized corneal opacities have been a challenge for opthalmologists because of the poor outcome. 101 patients with such high risk indications underwent penetrating keratoplasty. Some of them also underwent concurrent procedures like PC IOL implantation or vitrectomy. The patients' follow up period ranged from six months to four years. The results were evaluated. Good quality donor material, good intraoperative tissue handling, aggressive and meticulous postoperative management contributed to gratifying results. However chemical injuries and patients with dry eyes continued to have a bad prognosis and keratoplasty in these cases proved to be unrewarding. MJAFI 2001; 57 : 16-18

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Section: Discussionmentioning

confidence: 44%

Section: Discussionmentioning

confidence: 75%

Section: Introductionmentioning

confidence: 99%

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Penetrating Keratoplasty in High Risk Cases

Parihar

Rodrigues

Ramchandran

et al. 2001

Medical Journal Armed Forces India

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“…The use of corneal grafts in these situations carries poor prognosis; the risk of graft rejection is very high, which would necessitate immunosuppressive therapy with its potentially serious side effects. [21][22][23][24][25] Availability of donor material is another drawback of this technique. All the patients we managed experienced pain relief and were able to reduce the frequency of medication and duration of hospital stay and none developed a painful blind eye.…”

Section: Discussionmentioning

confidence: 99%

Superior forniceal conjunctival advancement pedicles (SFCAP) in the management of acute and impending corneal perforations

Sandinha

Zaher

Roberts

et al. 2005

Eye

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“…In Australia, only 31% of corneal grafts are performed for keratoconus and less than 1% are carried out for stromal dystrophies. 1 The majority of corneal transplants are carried out for acquired corneal conditions.…”

Section: Introductionmentioning

confidence: 99%

Management of high-risk corneal grafts

Coster¹,

Williams²

2003

Eye

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Corneal transplantation is not invariably successful despite the anterior chamber of the eye being an immunologically privileged site. Inflammation erodes privilege. Other than by reducing inflammation through meticulous surgery, careful postoperative surveillance, and effective topical corticosteroids in the postoperative phase, there is little that a surgeon can do to improve the outlook for the majority of patients receiving corneal transplants. For patients at appreciable risk, HLA Class I matching may help where it is available. So too will systemic immunosuppression where it can be justified. Despite these measures, the results of corneal transplantation have not shown the improvement seen in solid organ transplantation over the last 30 years. New approaches applicable to corneal transplantation are required.

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First Report of the Australian Corneal Graft Registry

Abstract: A full list of contributing surgeons appears at the end of the article.

Cited by 131 publications

References 15 publications

Penetrating Keratoplasty in High Risk Cases

Penetrating Keratoplasty in High Risk Cases

Superior forniceal conjunctival advancement pedicles (SFCAP) in the management of acute and impending corneal perforations

Management of high-risk corneal grafts

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