First report of the simultaneous occurrence of choroid plexus papilloma and meningioma in a dog

Abstract

A 7-year-old spayed female English Cocker Spaniel was examined because of a 1-week history of lethargy, stumbling over objects and circling, and the presence of two tonic-clonic generalised seizures two days before presentation. The neurological signs suggested a lesion involving the right forebrain. Computed tomography revealed the presence of two intracranial masses, one located inside the right lateral ventricle and the other located in the right frontal lobe attached to the falx cerebri. Because of the poor prognosis, the owner refused to continue with the therapy and the dog was euthanised. On postmortem examination one mass was diagnosed histologically as a meningioma and the other as a papilloma of the choroid plexus. Information in the veterinary literature on multiple malignancies affecting the central nervous system is very limited. To the best of the authors' knowledge, the association of meningioma and choroid plexus papilloma has never been reported either in the human or in the veterinary medical literature.

Clinical, magnetic resonance imaging, and histological description of a choroid plexus papilloma with disseminated intraventricular and spinal cerebrospinal fluid drop metastases in a young adult dog: a case report

“…Our patient is the youngest dog diagnosed with CPP. Depending on their intracranial location, reported clinical signs associated with CPP include epileptic seizures, vestibular syndrome, neck pain, and altered mentation and regurgitation (3,4,(19)(20)(21)(22)(23)(24). Our patient did not display any clinical signs consistent with intracranial disease.…”

“…According to the published literature in veterinary medicine, the median age of dogs diagnosed with CPP is 5 years (ranging from 3 to 14 years) (3,4,15,(17)(18)(19)(20)(21)(22)(23). Our patient is the youngest dog diagnosed with CPP.…”