First Report on
            <i>Schizophyllum commune</i>
            from a Dog

Kano, Rui; Oomae, Syougo; Nakano, Yasuhiro; Minami, Takeo; Sukikara, Michio; Nakayama, Takao; Hasegawa, Atsuhiko

doi:10.1128/jcm.40.9.3535-3537.2002

Cited by 25 publications

(25 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…2005). Schizophyllum commune is also an emerging pathogen of mammals and humans, with reports of bone and soft tissue infection in dogs (Kano et al., 2002, Tanaka et al., 2008), and sinusitis and infections of soft tissue, lung and nails in humans, although largely in immunocompromised patients (Chowdhary et al., 2013, Tsukatani et al., 2015). Most recently, S. commune has been isolated from an infected harbour seal (Hanafusa et al.…”

Section: Model Agaricomycetesmentioning

confidence: 99%

The good, the bad and the tasty: The many roles of mushrooms

Mattos-Shipley¹,

Ford²,

Alberti³

et al. 2016

Studies in Mycology

View full text Add to dashboard Cite

Fungi are often inconspicuous in nature and this means it is all too easy to overlook their importance. Often referred to as the “Forgotten Kingdom”, fungi are key components of life on this planet. The phylum Basidiomycota, considered to contain the most complex and evolutionarily advanced members of this Kingdom, includes some of the most iconic fungal species such as the gilled mushrooms, puffballs and bracket fungi. Basidiomycetes inhabit a wide range of ecological niches, carrying out vital ecosystem roles, particularly in carbon cycling and as symbiotic partners with a range of other organisms. Specifically in the context of human use, the basidiomycetes are a highly valuable food source and are increasingly medicinally important. In this review, seven main categories, or ‘roles’, for basidiomycetes have been suggested by the authors: as model species, edible species, toxic species, medicinal basidiomycetes, symbionts, decomposers and pathogens, and two species have been chosen as representatives of each category. Although this is in no way an exhaustive discussion of the importance of basidiomycetes, this review aims to give a broad overview of the importance of these organisms, exploring the various ways they can be exploited to the benefit of human society.

show abstract

Section: Model Agaricomycetesmentioning

confidence: 99%

The good, the bad and the tasty: The many roles of mushrooms

Mattos-Shipley¹,

Ford²,

Alberti³

et al. 2016

Studies in Mycology

View full text Add to dashboard Cite

show abstract

“…However, it has been reported to be an etiological agent of other types of infections and conditions, such as a brain abscess (16,17), meningitis (18), an eye infection (19), palate ulceration (20), and onychomycosis (21). Infections have also been reported in other mammals (22)(23)(24) and in both immunocompromised and immunocompetent individuals (25,26).…”

mentioning

confidence: 99%

Schizophyllum radiatum, an Emerging Fungus from Human Respiratory Tract

et al. 2016

View full text Add to dashboard Cite

Schizophyllum is an important genus of basidiomycetes that, apart from being of genetic and biotechnological interest, is also reported to be a plant and animal pathogen. Schizophyllum commune is the best-known species and the only one reported from clinical specimens thus far, being recovered mainly from the respiratory tract. The aim of this study was to determine the species diversity of 23 clinical isolates of Schizophyllum from the United States using multilocus phylogenetic analysis and their in vitro susceptibilities to six drugs. The markers used for sequencing were the internal transcribed spacer (ITS), a portion of the nuclear large subunit (LSU) of ribosomal DNA, the RNA polymerase II second-largest subunit (RPB2), and the translation elongation factor 1␣ (EF-1␣) gene. The analyses revealed that 22 of the clinical isolates were in the Schizophyllum radiatum clade with high support values and 1 isolate was in the S. commune clade. This is the first report of this species in clinical samples. The two species mentioned above showed very similar morphological features in culture (i.e., white, cottony, unsporulated colonies composed of hyphae with clamp connections), making morphological discrimination between the two impossible. An epitype is designed for S. radiatum, and its sequences have been deposited in GenBank. The antifungal that showed the greatest in vitro activity against the strains tested was shown to be amphotericin B. In general, the strains of S. radiatum showed higher MICs than S. commune. S chizophyllum (Schizophyllaceae, Agaricales) comprises one of the most commonly found mushrooms on the planet (1). The most common species of the genus is Schizophyllum commune, a ubiquitous fungus well-known as a wood decay organism able to cause white rot (1, 2) but also by its biotechnological applications (3). It has been used as an ethanol producer (4), and some of its metabolites have anticancer (5) and antimicrobial (6, 7) properties. It also has been studied for many years as a model for understanding mating interactions (8, 9). In recent years, S. commune has become clinically relevant as an etiological agent of respiratory infections in humans (10-15). However, it has been reported to be an etiological agent of other types of infections and conditions, such as a brain abscess (16, 17), meningitis (18), an eye infection (19), palate ulceration (20), and onychomycosis (21). Infections have also been reported in other mammals (22-24) and in both immunocompromised and immunocompetent individuals (25,26).The most effective treatment options for infections by S. commune are yet to be determined, although various treatment modalities have been used (14,(25)(26)(27)(28)(29). Most susceptibility patterns for these fungi are restricted to individual cases; however, studies by Gonzalez et al. (30) and Chowdhary et al. (31) with 5 and 26 strains, respectively, indicated that amphotericin B (AMB), itraconazole (ITC), and voriconazole (VRC) had good in vitro activity against the isolates tested, while elev...

show abstract

“…Even the one exceptional case of mycelium brain abscess was likely the result of dissemination from a granulomatous lesion in the lungs. Among canines, thus far only one report has been published, a cervical granulomatous lesion due to S. commune infection [6]. As is the case with humans, identification of the pathogen is difficult.…”

mentioning

confidence: 99%

Basidiomycosis: Schizophyllum commune Osteomyelitis in a Dog

Tanaka¹,

Takizawa

Baba³

et al. 2008

J. Vet. Med. Sci.

View full text Add to dashboard Cite

ABSTRACT. A six-year-old female Labrador retriever dog was suffering from osteomyelitis in her hindlimb. A puncture wound caused by a rotted bamboo stick was presumed as the source of infection. The dog suffered from pre-existing aortic stenosis, but otherwise exhibited no significant abnormality in her systemic conditions excluding claudication of the left hindlimb. The results of cytology and pathological examinations of biopsy samples revealed the diagnosis of mycotic osteomyelitis in this dog. Mycological and DNA tests showed the pathogen as the mushroom Schizophyllum commune. Antibiotic sensitivity testing also revealed susceptibility to itraconazole, which was used to successfully treat the dog. This is a rare case of canine basidiomycosis with S. commune as the etiologic agent.

show abstract

First Report on Schizophyllum commune from a Dog

Cited by 25 publications

References 6 publications

The good, the bad and the tasty: The many roles of mushrooms

The good, the bad and the tasty: The many roles of mushrooms

Schizophyllum radiatum, an Emerging Fungus from Human Respiratory Tract

Basidiomycosis: Schizophyllum commune Osteomyelitis in a Dog

Contact Info

Product

Resources

About