First results of a highly granulated 3D CdTe detector module for PET

Chmeissani, M.; Kolstein, M.; Macias-Montero, Jose Gabriel; Puigdengoles, C.; Garcia, J.; Prats, X.; Martı́nez, Ricardo

doi:10.1088/1361-6560/aaa44c

Cited by 4 publications

(6 citation statements)

References 28 publications

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“…Both offer a relatively high stopping power (similar to the one offered by NaI:Tl scintillator crystals) and they can be operated at room temperature. Furthermore, with the use of highly granulated detectors high spatial, energy and time resolution can be achieved [88]. Table 5 summarizes important properties of some semiconductor materials used for medical imaging applications [80].…”

Section: Detector Technology For Ct Spect and Petmentioning

confidence: 99%

Hybrid Imaging: Instrumentation and Data Processing

et al. 2018

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State-of-the-art patient management frequently requires the use of non-invasive imaging methods to assess the anatomy, function or molecular-biological conditions of patients or study subjects. Such imaging methods can be singular, providing either anatomical or molecular information, or they can be combined, thus, providing "anato-metabolic" information. Hybrid imaging denotes image acquisitions on systems that physically combine complementary imaging modalities for an improved diagnostic accuracy and confidence as well as for increased patient comfort. The physical combination of formerly independent imaging modalities was driven by leading innovators in the field of clinical research and benefited from technological advances that permitted the operation of PET and MR in close physical proximity, for example. This review covers milestones of the development of various hybrid imaging systems for use in clinical practice and small-animal research. Special attention is given to technological advances that helped the adoption of hybrid imaging, as well as to introducing methodological concepts that benefit from the availability of complementary anatomical and biological information, such as new types of image reconstruction and data correction schemes. The ultimate goal of hybrid imaging is to provide useful, complementary and quantitative information during patient work-up. Hybrid imaging also opens the door to multi-parametric assessment of diseases, which will help us better understand the causes of various diseases that currently contribute to a large fraction of healthcare costs.

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Section: Detector Technology For Ct Spect and Petmentioning

confidence: 99%

Hybrid Imaging: Instrumentation and Data Processing

et al. 2018

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“…The Voxel Imaging PET Pathfinder project has developed a Proof-of-Concept (PoC) PET scanner with high spatial and energy resolutions [23]. As shown in figure 1, the PoC scanner is a ring-shaped device of 130 mm in diameter, consisting of 18 CdTe detector modules with an axial field of view (FOV) of 27 mm.…”

Section: Design Of the Proof-of-concept Prototype Scannermentioning

confidence: 99%

“…Each of the 18 PoC detector modules, as shown in figure 1, is a stack of 10 layers where each layer has 4 CdTe pixel sensors. The CdTe pixel sensor is a hybrid assembly of pixelated CdTe detectors produced with Schottky contacts [24,25] by Acrorad LTD, Japan and connected to a dedicated pixel ASIC [23] with solder bump balls. Each sensor has an array of 10 × 10 pixel electrodes with a pixel pitch of 1 mm and a 2 mm thickness of CdTe.…”

Section: Design Of the Proof-of-concept Prototype Scannermentioning

confidence: 99%

Tracking a moving point source using triple gamma imaging

Chmeissani,

Kolstein,

Ariño-Estrada

et al. 2024

J. Inst.

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With positron emission tomography (PET), the positron of a β + emitter radioisotope annihilates with a nearby electron producing a pair of back-to-back 511 keV gamma rays that can be detected in a scanner surrounding the point source. The position of the point source is somewhere along the Line of Response (LOR) that passes through the positions where the 511 keV gammas are detected. In standard PET, an image reconstruction algorithm is used to combine these LORs into a final image. This paper presents a new tomographic imaging technique to locate the position of a β + emitting point source without using a standard PET image reconstruction algorithm. The data were collected with a Proof-of-Concept (PoC) PET scanner which has high spatial and energy resolutions. The imaging technique presented in this paper uses events where a gamma undergoes Compton scattering. The positions and energies deposited by the Compton scattered gamma define the surface of a Compton cone (CC) which is the locus of all possible positions of the point source, allowed by the Compton kinematics. The position of the same point source is also located somewhere on the LOR. Therefore, the position of the point source is defined by the 3 gammas and is given by the intersection point of the LOR and the Compton cone inside the Field of View (FOV) of the scanner. We refer to this method as CC×LOR. This new technique can locate the point source with an uncertainty of about 1 mm, after collecting a minimum of 200 CC×LOR events.

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“…C, and the prior knowledge that the source is a uniform sphere of 250 m in diameter, we can derive the conditional probability, 𝑝(𝑫 |𝜶). The most probable system parameters, 𝜶 , can be found by constrained minimization process, 𝜶 = argmin{−𝑝(𝑫 𝒄 |𝜶)}, (10) which is performed in MATLAB [44] using the FMINCON function.…”

Section: E Experimental Calibration Of System Geometrymentioning

confidence: 99%

“…The Voxel imaging PET (VIP) system is another brain-dedicated system currently under construction, where each detector module consists of 4000 voxel channels. Preliminary simulation studies have been evaluated in [9] [10]. Mitchell, et al evaluated the energy resolution, intrinsic spatial resolution, time resolution, and sensitivity of a prototype PET scanner using strip CdTe detectors by simulation [11].…”

Section: Introductionmentioning

confidence: 99%

Experimental Evaluation of a 3-D CZT Imaging Spectrometer for Potential Use in Compton-Enhanced PET Imaging

Jin

Streicher

Yang

et al. 2023

IEEE Trans. Radiat. Plasma Med. Sci.

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We constructed a prototype positron emission tomography (PET) system and experimentally evaluated large-volume 3-D cadmium zinc telluride (CZT) detectors for potential use in Compton-enhanced PET imaging. The CZT spectrometer offers sub-0.5 mm spatial resolution, an ultrahigh energy resolution (~1% @ 511 keV) and the capability of detecting multiple gamma-ray interactions that simultaneously occurred. The system consists of four CZT detector panels with a detection area of around 4.4 cm × 4.4 cm. The distance between the front surfaces of the two opposite CZT detector panels is ~80 mm. This system allows us to detect coincident annihilation photons and Compton interactions inside the detectors and then exploit Compton kinematics to predict the first Compton interaction site and reject chance coincidences. We have developed a numerical integration technique to model the near-field Compton response that incorporates Doppler broadening, detector's finite resolutions, and the distance between the first and second interactions. This method was used to effectively reject random and scattered coincidence events. In the preliminary imaging studies, we have used point-sources, line-sources, a custom-designed resolution phantom and a commercial image quality (IQ) phantom to demonstrate an imaging resolution of approximately 0.75 mm in PET images, and Compton-based enhancement.

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First results of a highly granulated 3D CdTe detector module for PET

Cited by 4 publications

References 28 publications

Hybrid Imaging: Instrumentation and Data Processing

Hybrid Imaging: Instrumentation and Data Processing

Tracking a moving point source using triple gamma imaging

Experimental Evaluation of a 3-D CZT Imaging Spectrometer for Potential Use in Compton-Enhanced PET Imaging

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