First seizure in the older patient: Clinical features and prognosis

Lawn, Nicholas; Kelly, Andrew; Dunne, John W.; Lee, Judy; Wesseldine, Andrew

doi:10.1016/j.eplepsyres.2013.08.009

Cited by 35 publications

(32 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Importantly, the number of ER visits should not be interpreted as a marker for seizure-related injuries, since previous reports have found a low incidence of seizure-related injuries in the elderly (Lawn et al. 2013). In our material, we also detected similar rates of fractures and wounds in cases and controls, indicating that poststroke epilepsy does not contribute significantly to traumatic injuries in this group.…”

Section: Discussionmentioning

confidence: 99%

Clinical course of poststroke epilepsy: a retrospective nested case–control study

et al. 2015

View full text Add to dashboard Cite

IntroductionRecently, several epidemiological studies have demonstrated that epilepsy develops after approximately 10% of all cerebrovascular lesions. With an aging population, poststroke epilepsy is likely to be of increasing relevance to neurologists and more knowledge on the condition is needed. Patients with poststroke epilepsy are likely to differ from other epilepsy patient populations regarding age, side-effect tolerability, comorbidities, and life expectancy, all of which are important aspects when counselling newly diagnosed patients to make informed treatment decisions.MethodWe have here performed a nested case–control study on 36 patients with poststroke epilepsy and 55 controls that suffered stroke but did not develop epilepsy. The average follow-up time was between 3 and 4 years.ResultsIn our material, two-thirds of patients achieved seizure freedom and 25% experienced a prolonged seizure (status epilepticus) during the follow-up period. Cases consumed more health care following their stroke, but did not suffer more traumatic injuries. Interestingly, the mortality among cases and controls did not differ significantly. This observation needs to be confirmed in larger prospective studies, but indicate that poststroke epilepsy might not infer additional mortality in this patient group with considerable comorbidities.ConclusionsThe observations presented can be of value in the counselling of patients, reducing the psychosocial impact of the diagnosis, and planning of future research on poststroke epilepsy.

show abstract

Section: Discussionmentioning

confidence: 99%

Clinical course of poststroke epilepsy: a retrospective nested case–control study

et al. 2015

View full text Add to dashboard Cite

show abstract

“…This is an ongoing prospective study of patients with first-ever seizure seen by a hospital-based epilepsy service aiming to identify outcomes and risk factors for seizure recurrence. The methodology has been described previously 10 11. All patients seen between 2000 and 2011 with first-ever seizure, provoked or unprovoked, were included except those ineligible to drive because of age (<16 years) or disability.…”

Section: Methodsmentioning

confidence: 99%

“…Potential risk factors for seizure recurrence identified in prior first seizure studies2 11 15 16 were examined using Cox proportional hazards models. Independent variables analysed were age at first seizure, gender, family history of epilepsy, occurrence of the first seizure as a cluster or status epilepticus, seizure type, timing of seizure (awake vs asleep), seizure aetiology (including epileptogenic lesion on imaging), treatment and epileptiform abnormalities on EEG.…”

Section: Methodsmentioning

confidence: 99%

When is it safe to return to driving following first-ever seizure?

Brown

Lawn

Lee

et al. 2014

J Neurol Neurosurg Psychiatry

View full text Add to dashboard Cite

“…Las manifestaciones clínicas van a depender de acuerdo al tipo de convulsión, si esta es provocada versus no provocada, de la edad del paciente y si son convulsiones agudas versus convulsiones remotas sintomáticas (18 c) En la edad pediátrica por lo general la primera crisis es generalizada, se puede presentar a cualquier hora, siendo las causas más comunes las infecciones, traumatismo encéfalocraneanos, toxinas, problemas metabólicos y los trastornos del neurodesarrollo (20,21).…”

Section: Manifestaciones Clínicas De La Primera Crisis Afebrilunclassified

“…b. Electroencefalograma: El EEG registrado dentro de las primeras 24 a 48 horas de la crisis epiléptica puede evidenciar anormalidades hasta en un 70 % (24); sin embargo, en casi el 50% de EEG obtenidos y evaluados después de una primera crisis epiléptica serán normales, llegando hasta 80 % según otras publicaciones (21). Por otro lado, se registran anormalidades paroxísticas localizadas en un 34,9%, anormalidades inespecíficas (ondas lentas difusas o ausencia de elementos característicos de la fase de sueño) en un 8,3% y la presencia de actividad anormal en lóbulo frontal está más relacionada con recurrencia (25),así mismo, evaluaciones realizadas con video EEG de 24 horas informada como anormal podría tener un riesgo de recurrencia del 73,2% (26).…”

Section: Exámenes De Ayuda Al Diagnóstico En La Primera Crisis Afebrilunclassified

Manejo de primera crisis afebril:Importancia del enfoque clínico

Toro-Pérez¹,

Custodio

2017

Rev Neuropsiquiatr

View full text Add to dashboard Cite

RESUMENUna crisis epiléptica es un evento traumático físico como psicológico que plantea dificultades en el diagnóstico y muchas interrogantes para el tratamiento agudo y en el largo plazo. La recurrencia de una crisis epiléptica origina aún más serios y costosos problemas en la vida personal, familiar y laboral del individuo afectado. En estas circunstancias, un correcto abordaje del manejo de individuos con una primera crisis afebril debe ser una prioridad de los sistemas de salud con el objetivo fundamental de prevención de recurrencias. La elección de un fármaco antiepiléptico va a depender de una detallada anamnesis del evento clínico y de la información proveniente de estudios o tests neurofisiológicos y por exámenes de imágenes cerebrales.PALABRAS CLAVE: Anti-epilépticos, crisis epiléptica, diagnóstico, epilepsia, tratamiento. SUMMARYSeizures or an epileptic crisis is a traumatic event, both of physical and psychological nature that poses difficulties in the diagnostic process and many questions for its immediate and long-term management. The recurrence of an epileptic crisis causes even more serious and costly problems in the personal, family and work life of the affected individual. Due to this, a correct approach to the management of patients with a first afebrile crisis must be a priority of the health systems, with the primary purpose of preventing recurrences. The choice of an anti-epileptic drug will depend on a detailed anamnesis of the clinical event and onthe information from neurophysiological tests and brain imaging studies

show abstract

First seizure in the older patient: Clinical features and prognosis

Cited by 35 publications

References 27 publications

Clinical course of poststroke epilepsy: a retrospective nested case–control study

Clinical course of poststroke epilepsy: a retrospective nested case–control study

When is it safe to return to driving following first-ever seizure?

Manejo de primera crisis afebril:Importancia del enfoque clínico

Contact Info

Product

Resources

About