First Year Experience in Assisted Reproductive Technology  (ART) Services at IIUM Kuantan

Zainuddin, Assoc. Prof. Dr Ahmad Murad; Roszaman, R; Yw, Azantee; My, Hayati; Ma, Norsina; K., Siti

doi:10.31436/imjm.v12i1.1995

imjm

2013

DOI: 10.31436/imjm.v12i1.1995

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First Year Experience in Assisted Reproductive Technology (ART) Services at IIUM Kuantan

Assoc. Prof. Dr Ahmad Murad Zainuddin¹,

R Roszaman²,

Azantee Yw³

et al.

Abstract: Introduction: To analyze the ART outcome and factors associated with successful ART treatment for infertilecouples in a newly set up medical university IVF centre. Methods: A six-month cohort study of patients undergoing their first assisted reproductive technique cycle was conducted at IIUM fertility centre, Kuantan (from 15th June until 31st Dec 2009). Outcome measures include clinical pregnancy rate, ongoing pregnancy rate, take home baby rate and complications rate. Results: Fifty-five first cycles of IVF/… Show more

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2014

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Cited by 2 publications

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Is Assisted Reproductive Technique Shari’aa-compliant? A Case Study at a Fertility Centre in Malaysia

Sulaiman

et al. 2014

imjm

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Introduction: To investigate the questions that Muslim patients, embryologists, paramedics, clinical counsellor and doctors may have pertaining to the compliance of Assisted Reproductive Technique (ART) to Shari’aa. Methods: As a preliminary study, an open-ended survey was administered to participants. Participants for the survey comprised of 21 patients, 2 embryologists, 2 doctors, 4 paramedics and 1 counsellor. Results: Data analysis showed that most of the participants posed questions that fall into six classifications which are: Munakahat (Family Law), social Hukm, Fiqh Ibadah, Fiqh Qadha (Islamic Hukm), General Fiqh and Usul Fiqh. Conclusion: It is clear that even though the participants were rather familiar with some of the existing Fatwas pertaining to ART and IVF in Malaysia, there are still remaining doubts which need to be clarified. This indicates that there are challenges faced in seeking and providing ART treatment to Muslim patients. This needs to be addressed perhaps in the form of Shari’aa-compliant guidelines to provide a clear explanation of each process and procedure in fertility treatment.

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Is Assisted Reproductive Technique Shari’aa-compliant? A Case Study at a Fertility Centre in Malaysia

Sulaiman

et al. 2014

imjm

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Younger Women with Ovulation Disorders and Unexplained Infertility Predict a Higher Success Rate in Superovulation (SO) Intrauterine Insemination (IUI)

Viardot-Foucault

Tai

Prasath

et al. 2014

Ann Acad Med Singap

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Introduction: Superovulation-intrauterine insemination (SO-IUI) is the most common assisted reproductive technique (ART) in the world, with good evidence of efficacy and cost-effectiveness. However, parameters affecting its success have not been consistently reported. So in this study, we aim at determining the parameters influencing the success rate of SO-IUI. Materials and Methods: We conducted a retrospective cohort study of 797 SO-IUI cycles from 606 patients, performed between 2007 and 2009 in a single centre. These women received clomiphene citrate (CC), recombinant FSH (rFSH) or both. Results: There were 127 clinical pregnancies with a pregnancy rate (PR) of 15.9% (127/797) per treatment cycle. Factors associated with higher PR included maternal age <38 (P = 0.02), subfertility diagnoses of ovulatory disorders, unexplained infertility, sexual dysfunction and unilateral tubal obstruction (P = 0.02), an endometrial thickness ≥8 mm (P = 0.03), total number motile spermatozoa (TNMS) of ≥1 million (P = 0.03), and spermatozoa normal forms (NF) ≥4% (P <0.01) on bivariate analysis. When CC is used, the endometrial thickness is more likely to be suboptimal (<8 mm). All the above parameters remained significant except the subfertility diagnoses on multivariate analysis. Conclusion: Patients’ selection with women <38 years old and preferably with ovulation disorders and unexplained infertility is associated with the highest PR in SO-IUI. Cycle parameters such as the use of rFSH alone, with the avoidance of CC, TNMS ≥1 million and NF ≥4% is likely to result in the best outcomes and reduce the high order multiple pregnancy risk. Key words: Assisted reproductive technique, Fertility, Ovulation disorder, Predictive factors

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First Year Experience in Assisted Reproductive Technology (ART) Services at IIUM Kuantan

Cited by 2 publications

References 4 publications

Is Assisted Reproductive Technique Shari’aa-compliant? A Case Study at a Fertility Centre in Malaysia

Is Assisted Reproductive Technique Shari’aa-compliant? A Case Study at a Fertility Centre in Malaysia

Younger Women with Ovulation Disorders and Unexplained Infertility Predict a Higher Success Rate in Superovulation (SO) Intrauterine Insemination (IUI)

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