Mesopelagic species are the principal constituents of larval fish assemblages inhabiting the southerly California Current region. Seasonal larval abundance is influenced by circulation of the California Current and subtropical Countercurrent, including regional changes of the physical, chemical, and biological characteristics during the El Niñ o-Southern Oscillation. This study examines the mesopelagic fish larvae distribution and abundance patterns between seasons and years, with the aim of describing the mesopelagic larval assemblages during dynamic environmental changes induced by El Niñ o (1997)(1998) and the rapid transition to La Niñ a (1998)(1999)(2000) along the west coast of the Baja California Peninsula (25-31°N). Despite large oceanographic variability, larval assemblages varied principally on a seasonal basis, related to reproductive periods and the north-south gradient influenced by the seasonal pattern of the California Current. An increased diversity, number of species, and abundance of tropical species was noticeable during the northward expansion of warm-water taxa during El Niñ o, principally in the northern areas (Ensenada and Punta Baja). After El Niño, population adjustments and rapid recovery occurred during La Niñ a conditions, which reflected seasonal differences in the mesopelagic community structure that are closely related to the seasonal pattern of oceanic currents.