“Fishcide” effect of the fungicide difenoconazole in freshwater fish (Labeo rohita): A multi-endpoint approach

Nataraj, Bojan; Hemalatha, Devan; Malafaia, Guilherme; Maharajan, Kannan; Ramesh, Mathan

doi:10.1016/j.scitotenv.2022.159425

Cited by 15 publications

(3 citation statements)

References 74 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In carp, difenoconazole exposure might cause ROS production resulting in oxidative stress with increased MDA levels and subsequent decline in the activity level of enzymatic antioxidants such as CAT, SOD, and GPx ( Wu et al, 2023 ). Nataraj et al (2023) studied the effects of difenoconazole exposure in Labeo rohita. Among the various organs of Labeo rohita, such as gill, liver and kidneys examined for their antioxidant efficiencies, a significant reduction in the activities of SOD and CAT was observed in comparison with the control fish.…”

Section: Pesticides Induced Oxidative Stress In Fishesmentioning

confidence: 99%

Effects of microplastics, pesticides and nano-materials on fish health, oxidative stress and antioxidant defense mechanism

Subaramaniyam,

Allimuthu,

Vappu

et al. 2023

Front. Physiol.

View full text Add to dashboard Cite

Microplastics and pesticides are emerging contaminants in the marine biota, which cause many harmful effects on aquatic organisms, especially on fish. Fish is a staple and affordable food source, rich in animal protein, along with various vitamins, essential amino acids, and minerals. Exposure of fish to microplastics, pesticides, and various nanoparticles generates ROS and induces oxidative stress, inflammation, immunotoxicity, genotoxicity, and DNA damage and alters gut microbiota, thus reducing the growth and quality of fish. Changes in fish behavioral patterns, swimming, and feeding habits were also observed under exposures to the above contaminants. These contaminants also affect the Nrf-2, JNK, ERK, NF-κB, and MAPK signaling pathways. And Nrf2-KEAP1 signalling modulates redox status marinating enzymes in fish. Effects of pesticides, microplastics, and nanoparticles found to modulate many antioxidant enzymes, including superoxide dismutase, catalase, and glutathione system. So, to protect fish health from stress, the contribution of nano-technology or nano-formulations was researched. A decrease in fish nutritional quality and population significantly impacts on the human diet, influencing traditions and economics worldwide. On the other hand, traces of microplastics and pesticides in the habitat water can enter humans by consuming contaminated fish which may result in serious health hazards. This review summarizes the oxidative stress caused due to microplastics, pesticides and nano-particle contamination or exposure in fish habitat water and their impact on human health. As a rescue mechanism, the use of nano-technology in the management of fish health and disease was discussed.

show abstract

Section: Pesticides Induced Oxidative Stress In Fishesmentioning

confidence: 99%

Effects of microplastics, pesticides and nano-materials on fish health, oxidative stress and antioxidant defense mechanism

Subaramaniyam,

Allimuthu,

Vappu

et al. 2023

Front. Physiol.

View full text Add to dashboard Cite

show abstract

“…Moreover, the degree and extent of the alterations observed in the livers and spleens were evaluated by using a score value (a) ranging from 0 to 3 (0 = no alterations or very mild changes in <5% of fields; 1 = slight and localized modifications in <20% of fields; 2 = moderate and mild diffuse modifications in 20 to 60% of fields; 3 = severe and widespread modification in >60% of fields). This ranking was used by Nataraj et al [30] to define a general assessment value of the histopathological lesion in animal tissues. Using the factors of importance (ω) and score values (a), the histopathological alteration indices (HA) were calculated using the following equation:…”

Section: Histopathological Analysismentioning

confidence: 99%

A Deep Survey of Fish Health for the Recognition of Useful Biomarkers to Monitor Water Pollution

Orso,

Imperatore,

Coccia

et al. 2023

Environments

View full text Add to dashboard Cite

The aim of the present study was to evaluate the wild freshwater fish health status using a vast array of biomarkers as predictive factors of pollutant exposure. The European eel (Anguilla anguilla) and brown trout (Salmo trutta fario), resident in rivers with different degrees of pollution in the South of Italy (Picentino River with good environmental quality and Tusciano River with low environmental quality), were examined using biometric parameters, histopathological and immunohistochemical biomarkers to evaluate the health status and a possible correlation with the water quality. Several alterations identified in the liver positively correlated with water and soil pollutants: hemorrhage (p ≤ 0.05), cytoplasmic vacuolization (p ≤ 0.01), hemosiderosis (p ≤ 0.05), irregular arrangement of hepatocytes (p ≤ 0.01), lipid accumulation (p ≤ 0.05), necrosis (p ≤ 0.01), cellular hyperplasia (p ≤ 0.05), leukocyte infiltration (p ≤ 0.01) and melanomacrophages centers (MMC) (p ≤ 0.01). In the spleen, only hemosiderosis correlated with water and soil pollutants (p ≤ 0.05). The inflammatory biomarker tumor necrosis factor α (TNFα) and ciclooxigenase 2 (COX2) responded to the environmental pollution, as well as the oxidative stress biomarkers superoxide dismutase (SOD2) and 8-Hydroxy-2′-deoxyguanosine (8-OHdG). Erythrocytic nuclear abnormalities and erythrocytic cellular abnormalities were found to be significantly higher in the blood of both the European eel (p < 0.0001) and brown trout (p < 0.001) in the Tusciano River compared with the Picentino River. Taken together, these results outline the need to increase the number of suitable biomarkers to assess fish health and reinforce the importance of employing additional biomarkers in biomonitoring programs that can be applied to evaluate water quality and in environmental assessment around the world.

show abstract

“…Besides, heavy metal pollution exhibited genotoxicity in several fish species (Tlenshieva et al, 2022;Choudhury et al, 2023). On the other hand, pesticides contamination also negatively affect the larval development and growth (Nataraj et al, 2023); hemato-biochemical profiles (Rohani, 2023); cellular and nuclear structure of erythrocytes (Akter et al 2020;Khatib et al, 2022); functions of important organs such as gill, liver, kidney and gonad (Khabbazi et al, 2014;Farag et al, 2021;Shah and Parveen, 2022) of different fish species. Finally, aquatic organisms especially fish have become the unvoiced victims of these contamination as it is believed that aquatic systems act as final destination of all these contaminants.…”

mentioning

confidence: 99%

Pesticides and Heavy Metal Toxicity in Fish and Possible Remediation – A Review

Ghafarifarsani,

Fazle Rohani,

Raeeszadeh

et al. 2024

Annals of Animal Science

View full text Add to dashboard Cite

Pesticides and heavy metals are considered as potent contaminants in aquatic environment. Both contaminants are sourced into the aquatic ecosystems by various types of anthropogenic as well as natural practices. Such types of aquatic contamination drastically affect the normal activity of associated living organisms particularly fish. Both the pesticides and heavy metals toxicity cause several negative effects on fish growth, physiology, immune response, reproduction, embryonic and larval development as well as different histopathology of major organs including fish gill, kidney, liver, gonads, and intestine. Besides, the consumption of contaminated fish possess serious health concern to associated consumers. Considering these serious issues, the current review is designed to investigate the toxic effects of pesticides and heavy metals on different aspects of fishes along with their possible sources, major types, and mode of action as well as role of medicinal herbs to mitigate their toxicity.

show abstract

“Fishcide” effect of the fungicide difenoconazole in freshwater fish (Labeo rohita): A multi-endpoint approach

Cited by 15 publications

References 74 publications

Effects of microplastics, pesticides and nano-materials on fish health, oxidative stress and antioxidant defense mechanism

Effects of microplastics, pesticides and nano-materials on fish health, oxidative stress and antioxidant defense mechanism

A Deep Survey of Fish Health for the Recognition of Useful Biomarkers to Monitor Water Pollution

Pesticides and Heavy Metal Toxicity in Fish and Possible Remediation – A Review

Contact Info

Product

Resources

About