FISUL: A Framework for Detecting Adverse Drug Events from Heterogeneous Medical Sources Using Feature Importance

Abstract

Adverse drug events (ADEs) are considered to be highly important and critical conditions, while accounting for around 3.7% of hospital admissions all over the world. Several studies have applied predictive models for ADE detection; nonetheless, only a restricted number and type of features has been used. In the paper, we propose a framework for identifying ADEs in medical records, by first applying the Boruta feature importance criterion, and then using the top-ranked features for building a predictive model as well as for clustering. We provide an experimental evaluation on the MIMIC-III database by considering 7 types of ADEs illustrating the benefit of the Boruta criterion for the task of ADE detection.