Five-field IMRT class solutions and dosimetric planning guidelines for implementing accelerated partial breast irradiation

Quirk, Sarah; Grendarova, Petra; Roumeliotis, Michael

doi:10.1016/j.prro.2017.09.009

Cited by 14 publications

(28 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…When BMI was included as one of the physique indexes, we selected patients with a small physique (compared with European and or North American patients) [31]. However, when we evaluated the dosimetric parameters for the target and OARs, these values were clinically acceptable compared with the constraints set by previous studies [6][7][8]22,23].…”

Section: Discussionmentioning

confidence: 99%

“…The dose constraint of the ipsilateral lung was referenced in a previous report that used 3D-comformal radiotherapy (3DCRT) [22], and we were able to significantly reduce the dose using VMAT. Quirk et al presented more stringent recommendations (V 10% < 15% and V 30% < 5%) in five-field IMRT [23]. On introduction of VMAT, most of the plans have achieved not only our dose constraints but also Quirk's recommendations.…”

Section: Discussionmentioning

confidence: 99%

“…Previous trials have targeted Europeans and Americans women with relatively large physiques and breasts; however, this study investigated the feasibility of the VMAT-APBI treatment plan in Asian women with small physiques. For that reason, we performed the plan optimization using target and OAR dose constraints referred from studies including Europeans and Americans women (Table 2) [6][7][8]22,23].…”

Section: Vmat-apbi Planningmentioning

confidence: 99%

See 2 more Smart Citations

The influence of respiratory motion on dose distribution in accelerated partial breast irradiation using volumetric modulated arc therapy

et al. 2020

View full text Add to dashboard Cite

Accelerated partial breast irradiation (APBI) is alternative treatment option for patients with early stage breast cancer. The interplay effect on volumetric modulated arc therapy APBI (VMAT-APBI) has not been clarified. This study aimed to evaluate the feasibility of VMAT-APBI for patients with small breasts and investigate the amplitude of respiratory motion during VMAT-APBI delivery that significantly affects dose distribution. Methods: The VMAT-APBI plans were generated with 28.5 Gy in five fractions. We performed patient-specific quality assurance using Delta 4 phantom under static conditions. We also measured point dose and dose distribution using the ionization chamber and radiochromic film under static and moving conditions of 2, 3 and 5 mm. We compared the measured and calculated point doses and dose distributions by dose difference and gamma passing rates. Results: A total of 20 plans were generated; the dose distributions were consistent with those of previous reports. For all measurements under static conditions, the measured and calculated point doses and dose distributions showed good agreement. The dose differences for chamber measurement were within 3%, regardless of moving conditions. The mean gamma passing rates with 3%/2 mm criteria in the film measurement under static conditions and with 2 mm, 3 mm, and 5 mm of amplitude were 95.0 ± 2.0%, 93.3 ± 3.3%, 92.1 ± 6.2% and 84.8 ± 7.8%, respectively. The difference between 5 mm amplitude and other conditions was statistically significant. Conclusions: Respiratory management should be considered for the risk of unintended dose distribution if the respiratory amplitude is >5 mm.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Vmat-apbi Planningmentioning

confidence: 99%

See 1 more Smart Citation

The influence of respiratory motion on dose distribution in accelerated partial breast irradiation using volumetric modulated arc therapy

et al. 2020

View full text Add to dashboard Cite

show abstract

“…15 Class solutions have been used for technique comparison in breast treatment, 19,20 while a five-field IMRT template was established and evaluated on 40 patients treated with accelerated partial breast irradiation for left and right lesions. 21 The developed template was demonstrated to produce highly conformal and consistent treatment plans.…”

Section: Introductionmentioning

confidence: 99%

Automated planning through robust templates and multicriterial optimization for lung VMAT SBRT of lung lesions

Marrazzo

Arilli

Pellegrini

et al. 2020

J Applied Clin Med Phys

View full text Add to dashboard Cite

Purpose: To develop and validate a robust template for VMAT SBRT of lung lesions, using the multicriterial optimization (MCO) of a commercial treatment planning system. Methods: The template was established and refined on 10 lung SBRT patients planned for 55 Gy/5 fr. To improve gradient and conformity a ring structure around the planning target volume (PTV) was set in the list of objectives. Ideal fluence optimization was conducted giving priority to organs at risk (OARs) and using the MCO, which further pushes OARs doses. Segmentation was conducted giving priority to PTV coverage. Two different templates were produced with different degrees of modulation, by setting the Fluence Smoothing parameter to Medium (MFS) and High (HFS). Each template was applied on 20 further patients. Automatic and manual plans were compared in terms of dosimetric parameters, delivery time, and complexity. Statistical significance of differences was evaluated using paired two-sided Wilcoxon signed-rank test. Results: No statistically significant differences in PTV coverage and maximum dose were observed, while an improvement was observed in gradient and conformity. A general improvement in dose to OARs was seen, which resulted to be significant for chest wall V 30 Gy , total lung V 20 Gy , and spinal cord D 0.1 cc. MFS plans are characterized by a higher modulation and longer delivery time than manual plans. HFS plans have a modulation and a delivery time comparable to manual plans, but still present an advantage in terms of gradient. Conclusion: The automation of the planning process for lung SBRT using robust templates and MCO was demonstrated to be feasible and more efficient.

show abstract

“…Publications describing APBI techniques that meet major trial constraints with simple 3dimensional conformal techniques, and more recently advanced techniques for improved dosimetry, are available to support radiation planning. 8 Implementing an APBI fractionation of 27 Gy in 5 fractions can save a further 10, 11, or 20 treatment visits for select patients.…”

mentioning

confidence: 99%

Adapting Radiation Therapy Treatments for Patients with Breast Cancer During the COVID-19 Pandemic: Hypo-Fractionation and Accelerated Partial Breast Irradiation to Address World Health Organization Recommendations

Al-Rashdan

Roumeliotis

Quirk

et al. 2020

Advances in Radiation Oncology

Self Cite

View full text Add to dashboard Cite

Five-field IMRT class solutions and dosimetric planning guidelines for implementing accelerated partial breast irradiation

Cited by 14 publications

References 21 publications

The influence of respiratory motion on dose distribution in accelerated partial breast irradiation using volumetric modulated arc therapy

The influence of respiratory motion on dose distribution in accelerated partial breast irradiation using volumetric modulated arc therapy

Automated planning through robust templates and multicriterial optimization for lung VMAT SBRT of lung lesions

Adapting Radiation Therapy Treatments for Patients with Breast Cancer During the COVID-19 Pandemic: Hypo-Fractionation and Accelerated Partial Breast Irradiation to Address World Health Organization Recommendations

Contact Info

Product

Resources

About