Five‐Membered Heterocycles: Benzofuran and Related Systems

Transition-Metal-Free Synthesis of C3-Arylated Benzofurans from Benzothiophenes and Phenols

“…The benzofuran motif is a key structural unit found in a variety of functional molecules, from naturally occurring bioactive compounds to manmade organic electronics . Demand for this important subunit has resulted in a range of methods for its construction .…”

Synthesis of Fused and Linked Benzofurans from 2-Alkynylphenol Derivatives through Rhodium(I)-catalyzed Domino-type Addition Reactions

“…Benzo [b]furan is a privileged structural motif prevalently found in a variety of natural products and biologically active compounds. [1] Benzofuran derivatives have also received considerable attention as organic electronic materials in recent years. [2] 2-Alkynylphenols are readily accessible compounds that are suitable synthetic precursors of benzofurans.…”

“…Generation and reaction of (benzofuran-3-yl)rhodium(i) species ganic electronics and nanotechnology. [1,2] Herein, we report the results of our study on the synthesis of fused and linked benzofurans on the basis of the rhodium-catalyzed domino-type cyclization protocol.…”

Rhodium-Catalyzed Twofold Unsymmetrical C–H Alkenylation–Annulation/Thiolation Reaction To Access Thiobenzofurans

“…Benzofuran is a privileged molecular scaffold which exists in numerous natural products and bioactive compounds (Figure ). The transition-metal-catalyzed C–H functionalization of phenols with alkynes provides an efficient method for the preparation of benzofurans (Scheme a) . Despite remarkable progress, poor regioselectivity was observed when unsymmetrical dialkyl or diaryl acetylenes were employed.…”