Five-vessel umbilical cord and fetal outcome: an obstetric overview

Damiani, Gianluca Raffaello; Boca, Gregorio Del; Biffi, Anna

doi:10.1080/14767058.2021.1910660

Cited by 6 publications

(6 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Numerical abnormalities of umbilical cord vessels are rare and often overlooked during antenatal ultrasound scans. A case with 4 arteries and 1 vein in the umbilical cord has been reported [15], and the mother had a bicornuate uterus, suggestive of the associations between the numerical abnormality of umbilical cord vessels and maternal uterine anomalies. Another case has been reported with 2 arteries and 2 veins on the fetal side of the umbilical cord with 2 arteries and 1 vein on the placenta side [16].…”

Section: Double Umbilical Veinsmentioning

confidence: 95%

The Value of Antenatal Ultrasound in Diagnosing Anatomical and Morphological Abnormalities of the Fetal Umbilical Vein

Zhang,

Zhao,

Wang

et al. 2023

Clin. Exp. Obstet. Gynecol.

View full text Add to dashboard Cite

Background: Normally, fetal umbilical vein (UV) starts from the capillary network in the chorionic villus and accompanies the umbilical artery (UA). After leaving the placenta, it courses along within the umbilical cord. As the embryo develops, the proximal segment of both the right and left umbilical veins obliterate, and the distal end of the left umbilical vein enters the liver. The microvessels passing through the liver gradually merge and communicate with the hepatic sinus to form the ductus venosus, which then drains into the inferior vena cava (IVC). UV anatomical and morphological abnormalities in complex and variable forms often lead to poor fetal prognosis. In light of this, a thorough prenatal ultrasound providing detailed information on UV abnormalities is potentially clinically significant. Methods: The sonographic features and clinical data of fetuses diagnosed with abnormal umbilical vein anatomy and morphology by antenatal ultrasonography from January 2016 to December 2021 in Sichuan Provincial Maternity and Child Health Care Hospital were retrospectively analyzed. Results: A total of 403 fetuses were included in the study. Among them, 318 cases were diagnosed with intrahepatic persistent right umbilical vein, and 44 cases experienced intracardiac malformations, 34 cases with extracardiac malformations, and 14 cases with both intra-and extracardiac malformations. Three cases had double umbilical veins; 1 case with intracardiac malformation and 1 case with extracardiac malformation. Eighty cases were diagnosed with umbilical vein varix (manifested as intra-or extra-abdominal vein varix or umbilical vein aneurysm); 2 cases with intracardiac malformations and 11 cases with extracardiac malformations. Two cases were diagnosed with umbilical vein stenosis, with neither of them combined with other malformations. Among the 403 fetuses, 86 received genetic testing with 8 of them confirmed with chromosomal abnormalities and the remaining 78 being normal. Of the 8 cases, 7 were diagnosed with persistent right umbilical vein (PRUV) and 1 had umbilical vein stenosis. As related to pregnancy outcomes, 386 fetuses had no obvious abnormalities being observed during the subsequent 2 years' follow-up and 17 cases were terminated due to serious malformations. Conclusions: Antenatal ultrasound assists in the accurate diagnosis of anatomical and morphological abnormalities of the umbilical vein. For cases with no other malformations or chromosomal abnormalities, a better prognosis can be expected and careful follow-up is required, whereas for those with severe malformations or chromosomal abnormalities, the prognosis is often poor. Prenatal ultrasound should provide careful examination to determine whether the fetal umbilical vein has normal anatomy and morphology, thereby supporting better prenatal outcomes.

show abstract

Section: Double Umbilical Veinsmentioning

confidence: 95%

The Value of Antenatal Ultrasound in Diagnosing Anatomical and Morphological Abnormalities of the Fetal Umbilical Vein

Zhang,

Zhao,

Wang

et al. 2023

Clin. Exp. Obstet. Gynecol.

View full text Add to dashboard Cite

show abstract

“…The prenatal well as the postnatal examination of the placentas contributed significantly to the current knowledge of UC anomalies and their impact on fetal outcome. Hence, the examination of the number of vessels in the UC has become a standard part of routine pre-natal ultrasonography as well as gross examination of the placenta [2].…”

Section: Five Vessel Umbilical Cord With Placental Chorangiosismentioning

confidence: 99%

“…The UC normally contains three vessels: two umbilical arteries (UA) and one umbilical vein (UV) [2]. The presence of more than three vessels, apart from those mentioned above is defined as supernumery umbilical vessels [4].…”

Section: Five Vessel Umbilical Cord With Placental Chorangiosismentioning

confidence: 99%

“…[1] Abnormalities of the UC, referring to its morphology, placental insertion, number of vessels and primary tumors, may have a direct impact on the perinatal outcome and may relate with fetal abnormalities. [2] Chorangiosis is an uncommon pathology seen in 5-6% of placentas, with its incidence increasing with the gestational age. It is known to occur as an adaptive response to chronic placental hypoxia and has been found to be associated with various maternal, fetal and placental disorders.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Five too many! A Case of Incidentally Detected Five Vessel Umbilical Cord Associated with Placental Chorangiosis

Jadhav,

Kashif,

Garud

2022

Ann of Pathol and Lab Med

View full text Add to dashboard Cite

Supernumery vessels are defined as presence of four or more vessels present within the umbilical cord. This condition may often accompany a poor pregnancy outcome and presence of congenital anomalies. They may be present in healthy fetuses. Chorangiosis is an adaptive response to in-utero hypoxia and its presence signifies better pregnancy outcomes. Abnormalities that lead to multiple cord vessels are rare with the majority of reported cases highlighting four vessels due to a persistent right umbilical vein. Here, we report a case of a 5-vessel umbilical cord associated with chorangiosis of placenta, detected incidentally after birth.

show abstract

“…In our study, the use of IU in labor was well accepted by most patients and met with broad consensus, because it could reassure women in labor about their fetal condition as well as simplifying the understanding of the patient's management [6] , [7] , [8] .…”

Section: Introductionmentioning

confidence: 99%

Intrapartum ultrasound and mother acceptance: A study with informed consent and questionnaire

Malvasi,

Damiani,

Edoardo

et al. 2023

European Journal of Obstetrics & Gynecology and Reproductiv

Self Cite

View full text Add to dashboard Cite

Five-vessel umbilical cord and fetal outcome: an obstetric overview

Cited by 6 publications

References 7 publications

The Value of Antenatal Ultrasound in Diagnosing Anatomical and Morphological Abnormalities of the Fetal Umbilical Vein

The Value of Antenatal Ultrasound in Diagnosing Anatomical and Morphological Abnormalities of the Fetal Umbilical Vein

Five too many! A Case of Incidentally Detected Five Vessel Umbilical Cord Associated with Placental Chorangiosis

Intrapartum ultrasound and mother acceptance: A study with informed consent and questionnaire

Contact Info

Product

Resources

About