Five-year analysis of clinical presentations and predictors of stroke mortality in rural Southwestern Nigeria: A retrospective observational study

Ibrahim, Azeez Oyemomi; Shabi, Olabode Muftau; Agbesanwa, Tosin Anthony; Olowoyo, Paul

doi:10.1016/j.afjem.2021.10.005

Cited by 5 publications

(4 citation statements)

References 18 publications

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“…1 ). These articles included 17 prospective cohort studies; 37 – 53 11 retrospective cohorts; 54 – 64 and 33 cross-sectional studies. 65 – 97 The pooled sample size was 376 676 participants, including 97 737 participants admitted to the emergency department, and 278 939 admitted to medical wards.…”

Section: Resultsmentioning

confidence: 99%

“…The prevalence of stroke admissions was 6.8% (95% CI: 4.7–9.6; 17 studies) 41 , 48 , 53 , 55 , 57 , 59 , 70 , 73 , 74 , 81 , 84 – 87 , 91 , 94 , 95 in medical settings, and 5.4% (95% CI: 2.8–10.2; five studies) 54 , 75 , 88 , 93 , 98 in emergency departments. Of these 22 studies, eight used radiological imaging to confirm the diagnosis.…”

Section: Resultsmentioning

confidence: 99%

“…Of these 22 studies, eight used radiological imaging to confirm the diagnosis. 41 , 54 , 57 , 59 , 74 , 91 , 93 , 98 …”

Section: Resultsmentioning

confidence: 99%

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Un miembro del personal de la Building Foundation for Development ayuda a preparar suministros para su entrega a instalaciones sanitarias y campos de desplazados en Al Jazirah (Sudán), que actualmente acoge a desplazados internos que huyen del conflicto en Jartum (Sudán).

Spencer,

Rylance,

Quint

et al. 2023

Bull World Health Org

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Objective To estimate the prevalence of individual chronic conditions and multimorbidity among adults admitted to hospital in countries in sub–Saharan Africa. Methods We systematically searched MEDLINE®, Embase®, Global Index Medicus, Global Health and SciELO for publications reporting on patient cohorts recruited between 1 January 2010 and 12 May 2023. We included articles reporting prevalence of pre-specified chronic diseases within unselected acute care services (emergency departments or medical inpatient settings). No language restrictions were applied. We generated prevalence estimates using random-effects meta-analysis alongside 95% confidence intervals, 95% prediction intervals and I 2 statistics for heterogeneity. To explore associations with age, sex, country-level income status, geographical region and risk of bias, we conducted pre-specified meta-regression, sub-group and sensitivity analyses. Findings Of 6976 identified studies, 61 met the inclusion criteria, comprising data from 20 countries and 376 676 people. None directly reported multimorbidity, but instead reported prevalence for individual conditions. Among medical admissions, the highest prevalence was human immunodeficiency virus infection (36.4%; 95% CI: 31.3–41.8); hypertension (24.4%; 95% CI: 16.7–34.2); diabetes (11.9%; 95% CI: 9.9–14.3); heart failure (8.2%; 95% CI: 5.6–11.9); chronic kidney disease (7.7%; 95% CI: 3.9–14.7); and stroke (6.8%; 95% CI: 4.7–9.6). Conclusion Among patients seeking hospital care in sub-Saharan Africa, multimorbidity remains poorly described despite high burdens of individual chronic diseases. Prospective public health studies of multimorbidity burden are needed to generate integrated and context-specific health system interventions that act to maximize patient survival and well-being.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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Un miembro del personal de la Building Foundation for Development ayuda a preparar suministros para su entrega a instalaciones sanitarias y campos de desplazados en Al Jazirah (Sudán), que actualmente acoge a desplazados internos que huyen del conflicto en Jartum (Sudán).

Spencer,

Rylance,

Quint

et al. 2023

Bull World Health Org

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“…Among 309 patients confirmed by CT imaging to have experienced a stroke, the majority (90.2%) had a stroke for the first time. Atrial fibrillation was detected on ECG in 18.8% of the affected patients [42]. Alkali et al in their study reported an AF prevalence of 9.2% among patients presenting at the National Hospital Abuja with acute stroke [36].…”

Section: Af and Strokementioning

confidence: 92%

Exploring the Epidemiology of Atrial Fibrillation in Nigeria: A Focus on Atrial Fibrillation in Heart Failure Patients and Its Association With Stroke

Otabor,

Alaka,

Onwuzo

et al. 2024

Cureus

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Atrial fibrillation (AF) represents a significant global public health concern, particularly due to its association with adverse health outcomes such as stroke and heart failure. In Nigeria, where the burden of cardiovascular diseases is rising, understanding the prevalence and impact of AF is crucial for effective healthcare planning and intervention strategies.This review examines the epidemiology of AF in Nigeria, comparing it with global and African data. It explores demographic and regional variations, comorbidity factors, and the impact of AF on the healthcare system, mortality, and quality of life.Notably, the prevalence of AF in Nigeria generally falls just under 5%, but this figure rises to approximately 9% in stroke patients and 11-20% among those with heart failure (HF). Rheumatic heart disease (RHD) is identified as a significant AF risk factor within Africa, affecting around 20% of AF patients -a stark contrast to the 2% in North America. AF's association with higher mortality rates and functional deterioration highlights the urgent need for improved diagnostic and therapeutic approaches, alongside broader public health measures.In conclusion, the review emphasises the significant public health concern AF represents in Nigeria, especially among HF and stroke patients, and stresses the importance of tailored healthcare policies and interventions to mitigate AF's impact and improve patient outcomes.

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Impact of fever on the outcome non-anoxic acute brain injury patients: a systematic review and meta-analysis

Gouvêa Bogossian,

Salvagno,

Fiore

et al. 2024

Crit Care

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Background Fever is a common condition in intensive care unit (ICU) patients, with an incidence between 30 and 50% in non-neurological ICU patients and up to 70–90% in neurological ICU patients. We aim to perform systematic review and meta-analysis of current literature to assess impact of fever on neurological outcomes and mortality of acute brain injury patients. Methods We searched PubMed/Medline, Scopus and Embase databases following the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement, and we included both retrospective and prospective observational studies, interventional studies, and randomized clinical trials that had data on body temperature and fever during ICU admission. The primary endpoints were neurological outcome and mortality at any time. Secondary outcomes included: early neurological deterioration, delayed cerebral ischemia (DCI, only for patients with subarachnoid hemorrhage), large infarct or hemorrhage size, hemorrhagic transformation (only for patients with ischemic stroke). This study was registered in PROSPERO (CRD42020155903). Results 180 studies from 14692 records identified after the initial search were included in the final analysis, for a total of 460,825 patients. Fever was associated with an increased probability of unfavorable neurological outcome (pooled OR 2.37 [95% CI 2.08–2.71], I 2 :92%), death (pooled OR 1.31 [95% CI 1.28–1.34], I 2 :93%), neurological deterioration (pooled OR 1.10 [95% CI 1.05–1.15]), risk of DCI (pooled OR 1.96 [95% CI 1.73–2.22]), large infarct size (pooled OR 2.94 [95% CI 2.90–2.98]) and hemorrhagic transformation (pooled OR 1.63 [95% CI 1.34–1.97]) and large hemorrhagic volume (pooled OR 2.38 [95% CI 1.94–2.93]). Conclusion Fever was associated with poor neurological outcomes and mortality in patients with acute brain injury. Whether normothermia should be targeted in the management of all neuro critically ill patients warrants specific research. Supplementary Information The online version contains supplementary material available at 10.1186/s13054-024-05132-6.

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Five-year analysis of clinical presentations and predictors of stroke mortality in rural Southwestern Nigeria: A retrospective observational study

Cited by 5 publications

References 18 publications

Un miembro del personal de la Building Foundation for Development ayuda a preparar suministros para su entrega a instalaciones sanitarias y campos de desplazados en Al Jazirah (Sudán), que actualmente acoge a desplazados internos que huyen del conflicto en Jartum (Sudán).

Un miembro del personal de la Building Foundation for Development ayuda a preparar suministros para su entrega a instalaciones sanitarias y campos de desplazados en Al Jazirah (Sudán), que actualmente acoge a desplazados internos que huyen del conflicto en Jartum (Sudán).

Exploring the Epidemiology of Atrial Fibrillation in Nigeria: A Focus on Atrial Fibrillation in Heart Failure Patients and Its Association With Stroke

Impact of fever on the outcome non-anoxic acute brain injury patients: a systematic review and meta-analysis

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