Five-year follow-up of a posterior chamber phakic intraocular lens with a central hole for correction of myopia

Abstract

Purpose To evaluate intermediate and long-term visual outcomes and safety of a phakic intraocular posterior chamber lens with a central hole (ICL V4c) for myopic eyes. Methods Retrospective, consecutive case study of patients that uneventfully received a ICL V4c for myopia correction, with a 5-year postoperative follow-up. Department of Ophthalmology, Goethe University Frankfurt, Germany. Results From 241 eyes that underwent ICL implantation, we included 45 eyes with a mean age at surgery of 33 years ± 6 (18–48 years), with a 5 years follow-up. CDVA improved from 0.05logMAR ± 0.15 CDVA preoperatively to − 0.00 ± 0,07 at 5 years and did not change significantly from 3 to 5 years’ time (p = 0.266). The mean spherical equivalent (SE) improved from -10.13D ± 3.39 to − 0.45D ± 0.69. The change in endothelial cell count showed a mean decrease of 1.9% per year throughout the follow-up. Safety and efficacy index were 1.16 and 0.78, respectively. Cataract formation was seen in 2 of 241 eyes (0.8%), but in none of the 45 eyes that finished the 5-year follow-up. Conclusions Our data show a good intermediate and long-term stability, efficiency, and safety of ICL V4c phakic lenses in myopic eyes comparable to other known literature.

Bibliometric and visualized analysis of posterior chamber phakic intraocular lens research between 2003 and 2023

“…Multiple meta-analyses have demonstrated that ICL implantation can achieve comparable or superior effectiveness and safety in correcting moderate-to-high myopia compared with laser in situ keratomileusis (LASIK) and small incision lenticule extraction (SMILE) (5,(12)(13)(14)(15). Notably, several clinical follow-up studies conducted over 5 years have consistently demonstrated the favorable stability of ICL and TICL (16)(17)(18)(19). However, in super-high myopia cases with a diopter (D) < −12D, stability after ICL implantation may be slightly compromised, leading to continued myopia increase and axial growth (20,21).…”