Five-Year Follow-Up of the Argentine Randomized Trial of Coronary Angioplasty With Stenting Versus Coronary Bypass Surgery in Patients With Multiple Vessel Disease (ERACI II)

Abstract

At five years of follow-up, in the ERACI II study, there were no survival benefits from any revascularization procedure; however patients initially treated with CABG had better freedom from repeat revascularization procedures and from MACE.

Five-Year Outcomes in Patients With Left Main Disease Treated With Either Percutaneous Coronary Intervention or Coronary Artery Bypass Grafting in the Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery Trial

“…21 Significant increases in repeat revascularization were observed within 1 year after the index procedure. 10,11 The rate of repeat revascularization in the LM PCI subgroup at 5 years (26.7%) is consistent with other published randomized trials and registries comparing PCI-and CABG-treated LM patients (15.7-28.4% 2,3,[14][15][16][17][18][19] ) but was higher in the CABG LM cohort (15.5%) compared with these studies (3.2-8.4%). 2,3,[14][15][16][17][18][19] In the patient population analyzed, the increased likelihood of repeat revascularization with PCI is a tradeoff; CABG has an increased stroke rate.…”

“…10,13 However, consistent with other randomized trials and nonrandomized registries of LM patients, mortality was similar in both treatment groups at 5 years. 1,3,[14][15][16][17][18][19] Only 1 propensity matched registry found increased mortality in LM patients treated with drug-eluting stents compared with CABG. 2 Procedure-related stroke is a serious and well-known complication after CABG.…”

Effects of Age and Sex on Clinical Outcomes After Percutaneous Coronary Intervention Relative to Coronary Artery Bypass Grafting in Patients With Triple-Vessel Coronary Artery Disease

“…[1][2][3][4][5][6][7][8][9] However, the subsequent trials in the era of drug-eluting stents (DES), in which mostly high-risk patients with diabetes mellitus or triple-vessel CAD were enrolled, have demonstrated significantly lower mortality after CABG compared with PCI. [10][11][12][13] We also have reported the better long-term outcomes in terms of all-cause death and myocardial infarction (MI) after CABG than after PCI in the all-comer CREDO-Kyoto (Coronary Revascularization Demonstrating Outcome Study in Kyoto) registry Cohort-1 and Cohort-2 in the era of BMS and DES, respectively.…”

Cost-Effectiveness of Percutaneous Coronary Intervention With Drug-Eluting Stents Versus Bypass Surgery for Patients With 3-Vessel or Left Main Coronary Artery Disease

“…In general, these studies have demonstrated similar short-and long-term mortality with either procedure (with the exception of diabetic patients) but substantial advantages of CABG in terms of angina relief and the need for subsequent revascularization procedures. [2][3][4][5][6][7][8] Economic evaluations performed in both the balloon angioplasty and bare metal stent eras have consistently demonstrated early cost savings with PCI but similar long-term costs for the 2 strategies. 7,9,10 Clinical Perspective on p 1157…”