2011
DOI: 10.1017/s0033291711002303
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Five-year outcome of major depressive disorder in primary health care

Abstract: This prospective, naturalistic, long-term study of a representative cohort of primary care patients with depression indicated slow or incomplete recovery and a commonly recurrent course, which need to be taken into account when developing primary care services. Severity of depressive symptoms and substance use co-morbidity should be systematically evaluated in planning treatment.

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Cited by 46 publications
(67 citation statements)
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“…Although this difference may be explained by the comorbid status of MDD, other explanations are possible. In longitudinal studies, many patients with MDD tend to remit in the first few months of the disorder (Keller et al, 1992; O'Leary et al, 2000; Riihimaki et al, 2011). However, we also know that MDD patients with comorbid anxiety disorders show worse clinical outcomes (Sherbourne and Wells, 1997).…”
Section: ) Discussionmentioning
confidence: 99%
“…Although this difference may be explained by the comorbid status of MDD, other explanations are possible. In longitudinal studies, many patients with MDD tend to remit in the first few months of the disorder (Keller et al, 1992; O'Leary et al, 2000; Riihimaki et al, 2011). However, we also know that MDD patients with comorbid anxiety disorders show worse clinical outcomes (Sherbourne and Wells, 1997).…”
Section: ) Discussionmentioning
confidence: 99%
“…The clinical course of depression may be characterized by slow or incomplete recovery and recurrences of major depressive episodes (Riihimäki et al, 2011). Even among individuals who receive treatment, a chronic course of depression is associated with poorer functioning in multiple domains (Pettit et al, 2009).…”
Section: Life Stressors and Resources And The 23-year Course Of Deprementioning
confidence: 99%
“…[13] Notably, several studies have used mixture models in treatment trials [14][15][16][17][18][19] and cohort studies. [20] Despite the use of similar techniques, the number of identified course groups varied (2)(3)(4)(5). This could be explained by differences in numbers of follow-ups (7 [14] to 24 [20]), interval lengths (1 week [18] to 3 months [14]), and instruments.…”
Section: Introductionmentioning
confidence: 99%