Let G be a finite simple group of Lie type and let P be a Sylow 2-subgroup of G. In this paper, we prove that for any nontrivial element x ∈ G, there exists g ∈ G such that G = P, x g . By combining this result with recent work of Breuer and Guralnick, we deduce that if G is a finite nonabelian simple group and r is any prime divisor of |G|, then G is generated by a Sylow 2-subgroup and a Sylow r-subgroup.