Flaccid Paralysis of the Limbs After an Asthmatic Attack

Severe enterovirus 68 respiratory illness in children requiring intensive care management

“…Additionally, past reports of Hopkins' syndrome, first described in the early 1970s, raised concern for the development of acute flaccid paralysis in conjunction with or shortly after a steroid-treated asthma exacerbation [34][35][36]. However, in the last 30 years, inhaled and oral corticosteroids have been established as the mainstay of therapy for children with asthma.…”

Monocrural flaccid paralysis following asthmatic attack (post asthmatic amyotrophy) – case report & minireview

“…Many postulations like viral infections, atopy and multifactorial immune suppression have been implicated [2,3]. The prognosis for recovery is generally considered poor in these cases.…”

“…The imaging did not reveal any abnormality of the L4,5 or S1 roots. In the management of this syndrome, various treatment options available are oral prednisone, pulse therapy with methylprednisolone, plasmapheresis and intravenous immunoglobulins [2].…”

“…It is a rare disorder, only few cases being reported in literature. It is a poliomyelitis like illness occurring 4-11 days after the onset of asthmatic attack[2], characterized by weakness and wasting of muscles, absent deep tendon and plantar reflexes, sensory system being not affected by the condition. The severity of asthmatic attack is not the criteria for development of HS.It may affect upper or lower limbs or both and manifest as monoplegia, diplegia or hemiparesis.…”

Differential Diagnosis of Acute Myelopathies: An Update

“…Exceedingly rare poliomyelitis-like pareses may occur suddenly in one or more limbs days after an asthma attack [18] associated with quite similar lesions. The pathogenesis is still under debate.…”