Flammer Syndrome-Eye Beyond Intraocular Pressure

Abstract

Objective: Flammer syndrome or Vascular dysregulation has nowadays become an important topic of debate since it is said to pose a risk in development of glaucomatous optic neuropathy, besides raised intraocular pressure. Our study was implemented to determine the role of flammer syndrome, far less known and often neglected in pathogenesis of glaucomatous optic neuropathy. Methods: The study group consisted of forty age and sex-matched diagnosed normal-tension glaucoma subjects and forty healthy controls. Each of them completed the Flammer syndrome questionnaire. T test was used for data analysis. Results: Statistically significant differences in symptoms like increased sensitivity (cold, drugs, smell, pain), long sleep onset time and a reduced feeling of thirst were existed between cases and control groups (p<0.001). They also demonstrated increased sensation to a few signs and symptoms like cold hands/feet, dizziness, migraines, headaches, and pain compared to controls but not significantly. Conclusion: The study could explain the possible relationship between normal-tension glaucoma and Flammer syndrome. Further research to be done to confirm this link in order to prevent the onset of glaucomatous optic neuropathy.

Antimicrobial evaluation and molecular docking studies of the combined ethanolic extract of Mollugo cerviana and Mukia maderspatana

“…( Figure 2 ) This formulation was highly effective against the bacterial strains when compared with the fungal strains. Earlier studies reveals that the plant extracts of Mollugo cerviana was effective against many gram positive and negative bacteria with the zone of inhibition of around 12mm to 30 mm [ 18 ] and the extracts of Mukia maderaspatina was highly effective against the bacterial strains with the inhibition zone ranging from 16mm to 22mm [ 19 ]. This gives clear evidence that the combination of these two extracts has a very good potent activity against the bacterial strains when compared with the individual extracts.…”