Flap-off Epi-LASIK Versus Automated Epithelial Brush in PRK: A Prospective Comparison Study of Pain and Reepithelialization Times

Magone, M. Teresa; Engle, Andrew T.; Easter, Thu Ha; Stanley, Philip Francis; Howells, James; Pasternak, Joseph F.

doi:10.3928/1081597x-20120921-02

Cited by 17 publications

(6 citation statements)

References 21 publications

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“…12 Another technique is the use of epikeratome for epithelial removal and replacement after excimer treatment (epi on LASEK); however, the speed of wound healing was not much different from previously described techniques. 13 There are two methods of TransPRK: (1) two-step laser ablation which removes epithelium by phototherapeutic keratectomy (PTK) followed by the PRK for refractive correction and (2) single-step laser ablation where both the epithelium and stroma are ablated simultaneously. 14 Two laser platforms that can perform single-step TransPRK are SmartSurfACE (SCHWIND eye-techsolutions) and Streamlight (WaveLight Allegretto Wave Eye-Q Laser; Alcon Laboratories).…”

Section: Introductionmentioning

confidence: 99%

Two-Step Transepithelial Photorefractive Keratectomy with WaveLight EX500 Platform for Adolescents and Adults with Low to Moderate Myopia: A 12-Month Comparative Evaluation

Tangmonkongvoragul¹,

Supalaset²,

Tananuvat³

et al. 2021

OPTH

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Purpose: To compare the visual and refractive results obtained after two-step TransPRK using an EX500 excimer laser for low to moderate myopic correction in adolescents and adults. Patients and Methods: Retrospectively, 91 eyes of 52 patients were categorized into four groups based on age and level of myopia. The demographics, data of efficacy, safety, predictability, stability, and post-operative complications were evaluated at 1, 3, 6, and 12 months post-operatively. Results: At 1-month, adolescents with low myopia achieved the highest mean efficacy index (P =0.034). The efficacy indices continuously increased during the 1-year follow-up in all groups, except in adolescents with moderate myopia. The highest safety and efficacy indices were recorded in adolescents with low myopia at 1-year. Post-operative spherical equivalent within ±0.50 D at 1 year was 48.75% of all treated eyes; however, the final mean refractive spherical equivalent (MRSE) was under-corrected in all groups. By month 3, the percentage of eyes that had grade 0.5 haze was most prevalent in adolescents with moderate myopia (P <0.001). Conclusion: two-step TransPRK using an EX500 proved to be an effective, predictable, stable and safe procedure for the correction of low to moderate myopia with or without astigmatism at 1 year. Adolescents with low myopia achieved the best-post-operative UDVA, efficacy and safety indices. Adolescents tolerated night visual problems and dry eye symptoms better than adults.

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Section: Introductionmentioning

confidence: 99%

Two-Step Transepithelial Photorefractive Keratectomy with WaveLight EX500 Platform for Adolescents and Adults with Low to Moderate Myopia: A 12-Month Comparative Evaluation

Tangmonkongvoragul¹,

Supalaset²,

Tananuvat³

et al. 2021

OPTH

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“…The mean time of epithelial healing was 6.16 ± 1.7 (3–14) days in the chilled and 6.10 ± 1.59 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 days in the room temperature group with no statistically difference between the two groups (p = 0.32). The mean BCVA one month after PRK were 0.013 ± 0.03 (0–0.22) logMAR and 0.014 ± 0.03 (0–0.22) logMAR in the chilled and room temperature groups, respectively, with no statistically significant difference between the groups (P = 0.84) ( Table 2 ).…”

Section: Resultsmentioning

confidence: 90%

“…The main cause of pain after PRK is baring of the corneal nerve after epithelial debridement, and it remains until epithelial repair occurs. For decreasing pain after PRK, various medical and surgical methods were suggested including: using bandage contact lens (BCL), dilute-tetracaine eye drops, 1 non-steroidal anti-inflammatory drugs (NSAIDs), 2 , 3 homatropine eye drops, 4 topical morphine, 5 transepithelial all surface laser ablation, 6 flap-off EPI-LASIK, 7 and LASEK. 8 …”

Section: Introductionmentioning

confidence: 99%

Efficacy of corneal cooling on postoperative pain management after photorefractive keratectomy: A contralateral eye randomized clinical trial

Zarei‐Ghanavati

Nosrat

Morovatdar

et al. 2017

Journal of Current Ophthalmology

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PurposeTo compare chilled and room temperature balanced salt solution (BSS) and bandage contact lens (BCL) on post photorefractive keratectomy (PRK) pain.MethodsIn a prospective, single-masked, controlled eye study, one hundred eyes of fifty patients were divided into two groups which received room temperature or chilled BSS and BCL in each eye, and compared for post-PRK pain. Three different pain evaluation systems were used to evaluate pain between the groups at 1 and 6 h and days 1, 2, 3, 5, and 7, postoperatively.Results15 patients were male (30%), and 35 were female (70%). The mean age was 29 ± 5 (20–40) y/o. The mean spherical equivalent (SE) of preoperative refractive error in both groups was not statistically significantly different (−4.18 ± 1.5 in chilled and −4.19 ± 1.7 in room-temperature groups, respectively; P = 0.94). The mean time of epithelial healing was 6.16 ± 1.7 (3–13) days in the chilled and 6.10 ± 1.59 (3–12) in the room temperature group (P = 0.32). Best corrected visual acuity (BCVA) at 1 month was 0.013 ± 0.03 (0–0.22) logarithm of the minimum angle of resolution (logMAR) in the chilled group and 0.014 ± 0.04 (0–0.22) logMAR in the room temperature group, postoperatively (P = 0.84). No statistically significant difference was found between the two groups by any of the three pain scoring systems. No clinically important corneal haziness was found in the groups during follow-up.ConclusionChilled BSS and BCL do not seem to be superior to room temperature in reducing post-PRK pain.

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“…They found that epi-LASIK and PRK had similar amounts of pain on postoperative day 1 with 19 of 20 (95%) patients reporting pain in both eyes, but patients that underwent epi-LASIK demonstrated statistically more pain than PRK patients on days 3 and 6. 23 Similarly, Magone et al 24 found that flap-off epi-LASIK led to significantly less postoperative pain on days 1, 2, 3, and 4 when compared with automated epithelial brush PRK.…”

Section: ' Introductionmentioning

confidence: 96%

Postoperative Pain After Laser Refractive Surgery

Benatti¹,

Afshari²

2016

International Ophthalmology Clinics

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Flap-off Epi-LASIK Versus Automated Epithelial Brush in PRK: A Prospective Comparison Study of Pain and Reepithelialization Times

Abstract: The flap-off group showed a statistically but not clinically significant advantage over the brush group in pain scores. However, no difference was noted in the percentage rate of epithelial healing time between the two groups.

Cited by 17 publications

References 21 publications

Two-Step Transepithelial Photorefractive Keratectomy with WaveLight EX500 Platform for Adolescents and Adults with Low to Moderate Myopia: A 12-Month Comparative Evaluation

Two-Step Transepithelial Photorefractive Keratectomy with WaveLight EX500 Platform for Adolescents and Adults with Low to Moderate Myopia: A 12-Month Comparative Evaluation

Efficacy of corneal cooling on postoperative pain management after photorefractive keratectomy: A contralateral eye randomized clinical trial

Postoperative Pain After Laser Refractive Surgery

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