With global climate change, cities face the challenge of increasing flood disaster caused by heavy rainfall, and the prediction and assessment of flood disaster risk is a crucial step towards risk mitigation and adaptation planning. In this study, a method combining Bayesian network (BN) model and geographic information system (GIS), which can capture the potential relationships between factors impacting flood disaster and has capacity of quantifying uncertainty and utilizing both data and knowledgebased sources, was proposed to assess flood disaster risk. The proposed methodology was applied in a case study to assess flood disaster risk and to diagnose the reason for flood disaster in Zhengzhou City, and the results were validated by comparing with actual situation. The results show that that the relative error of very-low, low, moderate, high and very-high risk predicted by the proposed model is 12.57%, 13.21%, 2.23%, 19.63% and 21.65%, respectively, which demonstrates the discriminative power of the established model. Based on the spatial distribution of different risk levels, it can be recognized that the flood disaster risk in Zhengzhou City is decreasing from the middle to the surroundings. The results provide some basis for the field control and management of urban flood disaster.