Flavanoids and Pterocarpans from the Bark of Erythrina fusca

Abstract

A and B (11a, b), one chalcone, isobavachalcone (12), and one isoflavone, wighteone (13), were isolated from the bark of Erythrina fusca LOUR. Their structures were elucidated on the basis of spectroscopic data. Some isolates were tested for antiplasmodial and cytotoxic activities and it was found that 5 and 9 exhibited moderate antiplasmodial activity against Plasmodium falciparum. For cytotoxicity, compounds 1, 4, 5, 9 and 12 showed moderate to weak activity against KB, BC and NCI-H187 cells, whereas 2 exhibited only weak activity against KB cells.

Flavonoid Constituents of Phlomis (Lamiaceae) Species Using Liquid Chromatography Mass Spectrometry

“…() and Innok et al . (). Moreover, other fragment ions in RT = 28.931 (Table ) and RT = 28.586 were based on reference standards (Wang et al ., ; Innok et al ., ).…”

“…(). Moreover, other fragment ions in RT = 28.931 (Table ) and RT = 28.586 were based on reference standards (Wang et al ., ; Innok et al ., ). It is notable that trihydroxyflavone derivatives were also reported in Ph.…”

Bactericidal and cytotoxic effects of Erythrina fusca leaves aquadest extract

“…8 Beside that, alkaloid is known as the compound to be a DNA intercalator and an inhibitor of DNA synthesis through topoisomerase inhibition. [17][18][19] In order to ensure this mechanism, further research need to be conducted. There were several cytotoxicity studies on Erythrina species.…”

Chemical constituents and biological activities ofAlbizia myriophyllawood

“…Both 4 and 5 were previously reported to be active against P-388 leukemia cell (Mahidol et al, 1997(Mahidol et al, , 2002. Compound 5 also possesses strong to moderate activity against KB, BC, and NCI-H187 cancer cell lines (Innok et al, 2009). The cytotoxic activity of 5 against KB cells in this study was in accordance with that previously described (Sutthivaiyakit et al, 2009).…”