Flavobacterium meningosepticum infection: an epidemiological study in a newborn nursery.

Thong, M L; Puthucheary, S. D.; Lee, E L

doi:10.1136/jcp.34.4.429

Cited by 41 publications

(25 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Once seeded on the respiratory equipment, these organisms can colonize or infect the respiratory tract or invade other body sites. In the study reported by Thong et al 16 on infections due to F. meningosepticum in a newborn nursery, the organism was isolated from the cerebrospinal fluid of all patients and blood from three patients. Bacteremia and meningitis in neonates was also reported by other authors.…”

Section: Discussionmentioning

confidence: 99%

“…In some of the previous studies, F. meningosepticum was traced to environmental sources. 7,16 The organism was known to inhabit watery environments and even to resist a chlorine level of 100 mg/kg higher than that used in chlorination of municipal water supplies. 13 Although F. meningosepticum was frequently isolated from the hospital environment, 10,11 our previous routine and environmental screening for hospital-acquired infections since 1982 did not reveal this organism in our hospital environment.…”

Section: Discussionmentioning

confidence: 99%

“…All the specimens were cultured according to methods described before 16 on blood agar, MacConkey and modified Thayer Martin media and incubated aerobically at 37°C for two to seven days. Suspicious-looking colonies were picked and identified by API 20 NE (analytical profile index, Biomerieux, France).…”

Section: Methodsmentioning

confidence: 99%

See 2 more Smart Citations

Flavobacterium Meningosepticumin Intensive Care Units of a Teaching Hospital in Riyadh, Saudi Arabia

et al. 1997

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Flavobacterium Meningosepticumin Intensive Care Units of a Teaching Hospital in Riyadh, Saudi Arabia

et al. 1997

View full text Add to dashboard Cite

“…It is widely distributed in the environment, and is an opportunistic human pathogen [2]. It has been reported as a causative agent of meningitis in premature and newborn infants [3]. In adults, it has been isolated from cases of pneumonia, endocarditis and meningitis, usually in association with some underlying severe illness [4].…”

Section: Introductionmentioning

confidence: 99%

Elizabethkingia meningoseptica Bacteremia in an Immuno-competent Patient

Rao¹,

Dandamudi²,

Koppula³

2017

JCR

View full text Add to dashboard Cite

Background: Elizabethkingia meningoseptica infections are not common but are clinically important because the organism is naturally resistant to multiple antibiotics. A prompt diagnosis is important so as to give appropriate antibiotic treatment. Case Report: We report a case of central line associated Elizabethkingia meningoseptica infection in a patient who was admitted with recurrent oligodendroglioma and underwent right frontal craniotomy and surgical decompression of tumor. Conclusion: Elizabethkingia meningoseptica infection should always be considered in the etiological diagnosis of septicemia who do not respond to empirical therapy as this results in an inappropriate choice of antimicrobial therapy, which may lead to increased morbidity and mortality of patients infected by this pathogen.

show abstract

“…as an opportunistic nosocomial pathogen (6,14) and can generate disease in favouring hospital and individual conditions. Most cases of the disease concern neonatal meningitis with a degree of mortality of 57% (5,12,15,13), although it may also represent a rare cause of pneumonia, endocarditis, postsurgical bacteraemia, cellulite and abdominal infections in immunosuppressed patients (1)(2)(3)14). Therefore, immunosuppression, particular treatment and/or invasive surgical procedures, long-term care, use of a central venous catheter and prolonged and untargeted antibiotic prophylaxis are considered among the main risk factors (12,16).…”

Section: Introductionmentioning

confidence: 99%

Elizabethkingia meningosepticum: an emerging nosocomial pathogen in a critical patient with septicaemia

Panetta¹,

Greco²,

Costanzo

et al. 2017

Microbiol Med

View full text Add to dashboard Cite

SummaryWe describe a case of sepsis due to the non-fermenter Gram-negative bacillus Elizabethkingia meningosepticum in a patient (M, 23 y.o.) hospitalized at the Intensive Care and Critical Care Medicine suffering of a severe neurological disease and acute surgical abdomen, caused by suppurative peritonitis secondary to PEG removal. Two sets of blood cultures were collected at the time of persistent fever. The culture on chocolate and blood agar showed the presence of colonies with characteristic grey-shiny appearance and 1-2 mm in diameter. No growth was instead evident on Mac-Conkey agar. The Gram stain was performed, but the final identification of the isolate as E. meningosepticum was obtained by Vitek2 System, on the basis of growth characteristics, biochemical reaction results, and the peculiar antibiotic susceptibility profile. The identification was also confirmed by Vitek MS MALDI-TOF mass spectrometry instrument (bioMérieux, Marcy-l'Étoile, France). Results of susceptibility testing highlighted the resistance to most antibiotics useful against Gram-negative bacteria and a paradoxical susceptibility to those targeting mainly Gram-positives. The vancomycin and ciprofloxacin combined therapy improved the patient's conditions, with a complete resolution of the E. meningosepticum bacteraemia. Unfortunately, due to the onset of important clinical and surgical complications, the patient died as a result of a septic shock caused by a MDR Acinetobacter baummannii. The present work underline the importance of correct species identification in the case of E. meningosepticum, a rare bacterium whose unique antimicrobial susceptibility pattern, require an ad hoc therapeutic approach. IntroductionElizabethkingia meningosepticum is a non-fermenter Gram-negative bacillus isolated for the first time in 1959 by the American bacteriologist Elizabeth King, who studied nonclassified bacilli related to childhood meningitis. The bacterium, initially classified as Flavobacterium meningosepticum, was re-classified as Cryseobacterium meningosepticum in 1994 and subsequently, after phylogenetic studies, definitely categorized as E. meningosepticum in 2005 (3, 9, 8).Widespread in nature (fresh water, salt water, or soil), is an aerobic, non-fermenter, non-spore-forming and non-mobile, saprophiticus ubiquitous bacillus. Unlike many other non-fermenter bacteria (Flavobacterium and Cryseobacterium), E. meningosepticum grows well at 37°C on blood agar and chocolate agar (4, 7). The colonies appear very pale yellow or more often not pigmented (dissimilarly to all Chryseobacterium species, that produce a not diffusible yellow-orange pigment); their growth is not easily appreciable after 24 hours of incubation (1). The grey colour of the colonies on blood agar is due to protease and gelatinase production. They grow poorly on MacConkey agar and are unable to grow on colistin-nalidixic acid (CNA) agar due to the susceptibility to quinolones such as nalidixic acid (6,10,14).E. meningosepticum has a characteristic resistance to most antibio...

show abstract

Flavobacterium meningosepticum infection: an epidemiological study in a newborn nursery.

Cited by 41 publications

References 15 publications

Flavobacterium Meningosepticumin Intensive Care Units of a Teaching Hospital in Riyadh, Saudi Arabia

Flavobacterium Meningosepticumin Intensive Care Units of a Teaching Hospital in Riyadh, Saudi Arabia

Elizabethkingia meningoseptica Bacteremia in an Immuno-competent Patient

Elizabethkingia meningosepticum: an emerging nosocomial pathogen in a critical patient with septicaemia

Contact Info

Product

Resources

About