Flavonoid Biosynthesis

Jaganath, Indu Bala; Crozier, Alan

doi:10.1002/9781119991311.ch11

Cited by 12 publications

(8 citation statements)

References 125 publications

(109 reference statements)

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“…UV treatment can also increase the content of rosmarinic acid in Origanum vulgare [ 106 ]. Additionally, UV-B treatment increased the activity of the enzyme chalcone synthase (EC: 2.3.1.74), which is a key enzyme in the phenylpropanoid metabolism, catalyzing the conversion of p-coumaroyl-CoA and malonyl-CoA to naringenin chalcone, which is a precursor of flavonoids [ 115 ].…”

Section: Enhancement Of Flavonoid and Phenolic Acids Content In Ormentioning

confidence: 99%

Flavonoids and Phenolic Acids from Oregano: Occurrence, Biological Activity and Health Benefits

Gutiérrez‐Grijalva

Picos-Salas

Leyva‐López

et al. 2017

Plants

185

126

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Several herb species classified as oregano have been widely used in folk medicine to alleviate inflammation-related diseases, respiratory and digestive disorders, headaches, rheumatism, diabetes and others. These potential health benefits are partially attributed to the phytochemical compounds in oregano such as flavonoids (FL) and phenolic acids (PA). Flavonoids and phenolic acids are among the most abundant and most studied phytochemicals in oregano species. Epidemiological, in vitro and in vivo experiments have related long-term consumption of dietary FL and PA with a decreased risk of incidence of chronic diseases. The aim of this manuscript is to summarize the latest studies on the identification and distribution of flavonoids and phenolic compounds from oregano species and their potential antioxidant, anti-inflammatory and anti-cancer health benefits.

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Section: Enhancement Of Flavonoid and Phenolic Acids Content In Ormentioning

confidence: 99%

Flavonoids and Phenolic Acids from Oregano: Occurrence, Biological Activity and Health Benefits

Gutiérrez‐Grijalva

Picos-Salas

Leyva‐López

et al. 2017

Plants

185

126

View full text Add to dashboard Cite

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“…Today, most of the enzymes and genes of the flavonoid biosynthesis pathway have been characterized. , The interest in polyphenol research has now largely moved to their health benefits. Interestingly, efforts have been made by the research group of Dr. Ronald Quinn at Griffith University providing evidence of a common organization between the binding sites of natural products to their biosynthetic enzymes and their biological targets.…”

Section: Heritage Of Dr Ibrahim’s Research Activitiesmentioning

confidence: 99%

“…Altogether, the work of Dr. Ibrahim's group led to the suggestion that prenylation at positions 6, 8, and 3′ of isoflavones was catalyzed by different position-specific ■ HERITAGE OF DR. IBRAHIM'S RESEARCH ACTIVITIES Today, most of the enzymes and genes of the flavonoid biosynthesis pathway have been characterized. 90,91 The interest in polyphenol research has now largely moved to their health benefits. Interestingly, efforts have been made by the research group of Dr. Ronald Quinn at Griffith University providing evidence of a common organization between the binding sites of natural products to their biosynthetic enzymes and their biological targets.…”

Section: Age Of High-throughput Sequencing Makes It Possible Tomentioning

confidence: 99%

Journey in the Polyphenol Research World with Ragai Ibrahim

Barron

Laflamme

Luca

2020

J. Agric. Food Chem.

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Dr. Ragai K. Ibrahim, Professor Emeritus at Concordia University, Montréal, Canada, passed away on the November 19, 2017 at the age of 88 years. Dr. Ibrahim dedicated his entire professional life to polyphenols and spent most of his academic career (1967–1997) at the Department of Biology of Concordia University in Montréal. He has been an active member of the Groupe Polyphénols since the beginning. This paper is a tribute to Dr. Ibrahim from some of his former students. An overview of the evolution of polyphenol research since the late 1950s and the outstanding contribution that Dr. Ibrahim had to this topic is given. The input of Dr. Ibrahim’s research to the enzymology and genetics of polyphenol biosynthesis is discussed. Furthermore, the links between Dr. Ibrahim’s work and some aspects of modern studies on the health benefits of polyphenols are presented.

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“…Compounds that contain a phenylpropane structure are produced directly or indirectly through the phenylpropane metabolic pathway. Some intermediates produced in the phenylpropane metabolic pathway, such as coumaric acid, trans-cinnamic acid, ferulic acid, and sinapic acid, can be further converted into coumarin, chlorogenic acid, and CoA lipids to synthesize flavonoids, lignin, and other substances [14,15]. Previous studies have revealed that high contents of lignin, flavonoids, lignans, and products of other phenylpropionic acid-related synthetic pathways are not accumulated in the rhizome of ginger.…”

Section: Introductionmentioning

confidence: 99%

Metabolomic analysis of bioactive compounds in mature rhizomes and daughter rhizomes in ginger (Zingiber officinale)

Chen

Tang

et al. 2019

Preprint

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Background The bioactive compounds of ginger (Zingiber officinale), such as gingerols, diarylheptanoids, and flavonoids, are of importance to human health because of their anticancer, antioxidant, and anti-inflammatory properties. The daughter rhizomes arise from mature rhizomes, but the pungency and pharmacological quality of the two rhizome types differ substantially.Results In this study, a metabolomic analysis was performed to investigate the biosynthesis of major bioactive compounds in the mature rhizome (R) and daughter rhizome (DR) in ginger. A total of 1212 differentially accumulated metabolites with p < 0.05 and |fold change| ≥ 1 were identified, of which 399 metabolites were more highly accumulated in R samples than in DR samples, whereas 211

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Flavonoid Biosynthesis

Cited by 12 publications

References 125 publications

Flavonoids and Phenolic Acids from Oregano: Occurrence, Biological Activity and Health Benefits

Flavonoids and Phenolic Acids from Oregano: Occurrence, Biological Activity and Health Benefits

Journey in the Polyphenol Research World with Ragai Ibrahim

Metabolomic analysis of bioactive compounds in mature rhizomes and daughter rhizomes in ginger (Zingiber officinale)

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