Flavonoids from the leaves of Deguelia utilis (Leguminosae): structural elucidation and neuroprotective properties

Oliveira, Dalglish Gomes de; Almeida, Cecília M. C. de; Silva, Consuelo Yumiko Yoshioka e; Arruda, Mara Silvia Pinheiro; Arruda, Alberto C.; Lopes, Dielly Catrina Favacho; Yamada, Elizabeth Sumi; Costa, Everardo Andrade da; Filho, Arnaldo Jorge Martins; Silva, Milton

doi:10.1590/s0103-50532012005000065

Cited by 10 publications

(11 citation statements)

References 16 publications

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“…Biomass conversion is less energy demanding than water splitting. The use of glucose, glycerol, lignin, etc., as sacrificial agents, can reduce the electron/hole recombination rate and favour selectively the synthesis of high value‐added products , . There are still only a relative small number of materials that can efficiently photoreform biomass, and works dedicated to improving the efficiency of photocatalysts, especially under natural solar light irradiation, are useful.…”

Section: Introductionmentioning

confidence: 99%

Photocatalytic Solar Light H₂ Production by Aqueous Glucose Reforming

et al. 2018

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A series of tungsten and nitrogen doped Pt-TiO 2 samples were prepared with the aim to extend the TiO 2 absorption to the visible light region and to enhance the separation efficiency of the photogenerated electron/hole pairs. The physicochemical features of the powders were characterized by Xray diffraction (XRD), UV/Vis reflectance spectra, specific surface area (SSA) determinations, and transmission electron microscopy (TEM) analyses. The influence of the presence of different [a] "Schiavello

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Section: Introductionmentioning

confidence: 99%

Photocatalytic Solar Light H₂ Production by Aqueous Glucose Reforming

et al. 2018

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“…The phytochemical composition of L. utilis has been widely studied [31][32][33][34][35][36][37][38]. The most important compounds found in the leaves, stems, and roots are rotenone (44%), rotenolone (6.7%), deguelin (22%), and thephrosin (4.3%) [39], which are rotenoids-isoflavones with additional pyrane/furane rings.…”

Section: Resultsmentioning

confidence: 99%

Promising Potential of Lonchocarpus utilis against South American Myasis

Luzuriaga-Quichimbo

Salas

Cerón-Martínez

et al. 2019

Plants

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Traditional medicine is especially important in the treatment of neglected tropical diseases because it is the way the majority of populations of affected countries manage primary healthcare. We present a case study that can serve as an example that can be replicated by others in the same situation. It is about the validation of a local remedy for myasis in Amazonian Ecuador, which is contrasted by bibliographic chemical reviews and in silico activity tests. We look for scientific arguments to demonstrate the reason for using extracts of Lonchocarpus utilis against south American myasis (tupe). We provide a summary of the isoflavonoids, prenylated flavonoids, chalcones, and stilbenes that justify the action. We make modeling predictions on the affinity of eight chemical components and enzyme targets using Swiss Target Prediction software. We conclude that the effects of this extract can be reasonably attributed to an effect of the parasite that causes the disease, similar to the one produced by synthetic drugs used by conventional medicine (e.g., Ivermectine).

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“…35 -D. s pruceana [25] 36 -R = OCH 3 , D. rufes cens [9], D. utilis [4] 37 -R = H, D . rufes cens [5,9], D. utilis [5,20,23] D. utilis [6], D. rufescens [9] D. utilis [6], D. rufescens [5,9] D. rufes cens [9] O OH OCH 3…”

Section: Ochmentioning

confidence: 99%

“…Some of them are used by Amazon indigenous population due to its ictiotoxic properties, such as Deguelia duckeana, known as "cipó cururu" or "timbó" [3], D. utilis and D. rufescens var. urucu, commonly known as "timbó branco" and "timbó vermelho", respectively [4,5]. Their insecticide and ichthyotoxic activities are attributed to rotenoids presence in its roots [4].…”

Section: Introductionmentioning

confidence: 99%

“…urucu, commonly known as "timbó branco" and "timbó vermelho", respectively [4,5]. Their insecticide and ichthyotoxic activities are attributed to rotenoids presence in its roots [4]. Deguelia species are rich in polyphenolic which demonstrate many biological activities such as leishmanicidal [6], cytotoxic against Artemia salina [3], antitumoral [7], antioxidant [8], phytotoxicity [9], antimicrobial [10,11] and vasorelaxant effect [12], among others.…”

Section: Introductionmentioning

confidence: 99%

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