Flavonoids, Phenolic Acids and Coumarins from the Roots ofAlthaea officinalis

Abstract

From the roots of ALTHAEA OFFICINALIS two flavonoid glycosides were separated. Phenolic acids and coumarins were investigated chromatographically. The structures of the compounds were established on the basis of acid hydrolysis and spectroscopic methods (UV, (1)H-NMR, (13)C-NMR) as hypolaetin 8-glucoside and the new flavonoid sulphate - isoscutellarein 4'-methyl ether 8-glucoside-2''-SO (3)K.

Influence of the extraction solvent on antioxidant activity of Althaea officinalis L. root extracts

“…Content of some flavonoids like hypolaetin-8-glucoside, isoquercitrin, kaempferol, quercetin and naringenin in the roots of A. officinalis has been reported [26,28,29]. The phytochemical evaluation of the extracts in the present study showed higher total flavonoid content for the extracts obtained by extraction with lower ethanol concentration in the mixed solvent (E2 and E3) (Figure 4).…”

“…According to literature, the root extract contains phenolic acids, in particular caffeic, p-coumaric, ferulic, p-hydroxybenzoic, salicylic, syringic, p-hydroxyphenylacetic and vanillic acid [26]. Our results revealed that the extract received with the lowest ethanol concentration (E2) contained the maximum phenolic content.…”

Aqueous extracts and polysaccharides from Marshmallow roots (Althea officinalis L.): Cellular internalisation and stimulation of cell physiology of human epithelial cells in vitro

“…Other constituents are about 0.2% flavone glycosides (Gudej, 1990), phenolic acids, the coumarin scopoletin (Gudej, 1991), starch, pectin (Hänsel et al, 1992), and tannins. Traditional use of aqueous extracts for dry cough due to irritation of the oral, pharyngeal or gastric mucosa after oral application is related to the bioadhesive effects of the polysaccharides to the epithelial mucosa, protecting the irritated cells from local irritation.…”

Phytochemicals and Antioxidants

“…Federal Regulation,21 CFR 172.510. They contain many phenolic compounds and flavonoids, such as hypolaetin-8-g1ucoside, isoscutellarein 4'-methyl ether 8-g1ucoside-2'-sulfonate, caffeic acid, p-coumaric acid, ferulic acid, p-hydroxybenzoic acid, vanillic acid, syringic acid, and p-hydroxyphenylacetic acids (Gudej 1991). These compounds have some anti-inflammatory properties.…”