Flexible Antibacterial Coatings

Musil, J.

doi:10.3390/molecules22050813

Cited by 23 publications

(29 citation statements)

References 46 publications

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“…Recently, the MS route [110] has been used also to deposit coatings on textiles and catheters [111], implants [112] and on food packaging [2,113]. At the laboratory level, this technique allows the synthesis of thin films up to the micron scale, together with the possibility of mixing materials to obtain the desired functionality [44,111,114]. In short, the sputtering process is obtained by applying an electric field between two electrodes within a medium vacuum chamber (see the scheme in Figure 2a).…”

Section: Magnetron Sputteringmentioning

confidence: 99%

“…It is interesting to note that such films composed of a single element present good adhesion, as shown by the ASTM D3359 cellophane tape test on hard and flexible substrates. On the other hand, the mixing into the coating of elements needed to obtain killing activity against both GP and GN strains has raised the issue of the coating mechanical stability [44,56,[116][117][118]. Musil et al [44,118] suggested that in this kind of thin film, the relative content of the most efficient antibacterial metals, Ag and Cu, needs to be between 10% and 30%, and this almost always results in a strong reduction of its hardness and in a poor mechanical stability, in particular if the film thickness is on the order of hundreds of nm.…”

Section: Magnetron Sputteringmentioning

confidence: 99%

“…As a matter of fact, because of the their mode of action, NMs should be less prone in promoting resistance in bacteria as compared to antibiotics [40]. Therefore a major goal is finding appropriate materials that are able to kill bacteria, such as metal-based NPs [40][41][42][43], but also obtaining functional nanostructured surfaces and thin film coatings [44,45] that can limit the spread of bacteria through surfaces. These former aspects increase the level of challenge, since the nanomaterial is required to have (1) microbicidal activity against a wide number of multi-drug-resistant Gram negative (GN) and Gram positive (GP) pathogens; (2) tunable mechanical properties and adhesion, to tailor the NPs release and the film durability in different conditions; and (3) cost-effective, environmental friendly production methods with high throughput.…”

Section: Introductionmentioning

confidence: 99%

“…Many different routes have been explored to synthesize NMs and NPs, from deposition of polymeric films [19,21,45,[49][50][51] with incorporated bactericidal agents [21,[52][53][54][55], or metallic or oxide films [2,21,56,57], to metal decoration of nanostructures [58][59][60]. The strategies are based on wet synthesis (spin-coating [61], sol-gel [57,61,62]), photochemical [52], biological [63][64][65], biotechnological [24] and physical methods (laser ablation [66], magnetron sputtering (MS) [2,44,[67][68][69], gas phase beams [70,71]). Surprisingly, the literature available on nanostructured coatings obtained by physical methods is scarce.…”

Section: Introductionmentioning

confidence: 99%

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Antimicrobial Nanostructured Coatings: A Gas Phase Deposition and Magnetron Sputtering Perspective

et al. 2020

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Counteracting the spreading of multi-drug-resistant pathogens, taking place through surface-mediated cross-contamination, is amongst the higher priorities in public health policies. For these reason an appropriate design of antimicrobial nanostructured coatings may allow to exploit different antimicrobial mechanisms pathways, to be specifically activated by tailoring the coatings composition and morphology. Furthermore, their mechanical properties are of the utmost importance in view of the antimicrobial surface durability. Indeed, the coating properties might be tuned differently according to the specific synthesis method. The present review focuses on nanoparticle based bactericidal coatings obtained via magneton-spattering and supersonic cluster beam deposition. The bacteria–NP interaction mechanisms are first reviewed, thus making clear the requirements that a nanoparticle-based film should meet in order to serve as a bactericidal coating. Paradigmatic examples of coatings, obtained by magnetron sputtering and supersonic cluster beam deposition, are discussed. The emphasis is on widening the bactericidal spectrum so as to be effective both against gram-positive and gram-negative bacteria, while ensuring a good adhesion to a variety of substrates and mechanical durability. It is discussed how this goal may be achieved combining different elements into the coating.

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Section: Magnetron Sputteringmentioning

confidence: 99%

Section: Magnetron Sputteringmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Antimicrobial Nanostructured Coatings: A Gas Phase Deposition and Magnetron Sputtering Perspective

et al. 2020

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“…In recent years, hospitals and infected patients suffer from multiresistant pathogens, which become difficult to treat with a selection of classical antibiotics. It has been suggested to counteract pathogens with nanoparticles like silver and copper . While silver is indeed strongly toxic to the environment, there is great promise that copper coupled to cellulose and textiles may be selectively toxic toward pathogens …”

Section: Applications For Functionalized Cellulosementioning

confidence: 99%

Functionalized Cellulose for Water Purification, Antimicrobial Applications, and Sensors

Bethke

Palantöken

Andrei

et al. 2018

Adv Funct Materials

215

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As the most abundant natural polymer, cellulose presents a unique advantage for large-scale applications. To fully unlock its potential, the introduction of desired functional groups onto the cellulose backbone is required, which can be realized by either chemical bonding or physical surface interactions. This review gives an overview of the chemistry behind the state-of-the-art functionalization methods (e.g., oxidation, esterification, grafting) for cellulose in its various forms, from nanocrystals to bacterial cellulose. The existing and foreseeable applications of the obtained products are presented in detail, spanning from water purification and antibacterial action, to sensing, energy harvesting, and catalysis. A special emphasis is put on the interactions of functionalized cellulose with heavy metals, focusing on copper as a prime example. For the latter, its toxicity can either have a harmful influence on aquatic life, or it can be conveniently employed for microbial disinfection. The reader is further introduced to recent sensing technologies based on functionalized cellulose, which are becoming crucial for the near future especially with the emergence of the internet of things. By revealing the potential of water filters and conductive clothing for mass implementation, the near future of cellulose-based technologies is also discussed.not suitable for drinking water treatment in rural areas or not applicable on a large scale. Other methods involving materials which have high adsorption capacities for pollutants, for example activated charcoal have been explored. [27,28] Nevertheless, there are no universal adsorbents for all pollutants, meaning that superior alternatives are still required. In recent years, biodegradable adsorbents such as cellulose and chitosan have attracted much attention for the removal of heavy metals.In particular cellulose has a number of advantages, which include high abundance, low cost, easy access, nontoxicity and biodegradability. It is particularly suited for the removal of low concentrations of heavy metals which occur in contaminated ground or tap water. [26] Beyond the aspects of copper removal from water, in this review we indicate how the metal's increased toxicity for microbial life can present an advantage for medical applications. Moreover, we also take a closer look at further applications of functionalized cellulose, including catalysis and sensing, which can make a great impact regarding energy conversion and management. The inclusion of conductive cellulose sensors within the internet of things global network is of particular interest, since an accurate weather forecast can provide swift adjustments in the usage of the often intermittent renewable energy sources. In order to understand what confers functionalized cellulose its versatility for broad applications, we first exemplify the functionalization techniques on a molecular basis.

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ZnO-based antimicrobial coatings for biomedical applications

Puspasari

Ridhova

Hermawan³

et al. 2022

Bioprocess Biosyst Eng

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Rapid transmission of infectious microorganisms such as viruses and bacteria through person-to-person contact has contributed significantly to global health issues. The high survivability of these microorganisms on the material surface enumerates their transmissibility to the susceptible patient. The antimicrobial coating has emerged as one of the most interesting technologies to prevent growth and subsequently kill disease-causing microorganisms. It offers an effective solution a non-invasive, low-cost, easy-in-use, side-effect-free, and environmentally friendly method to prevent nosocomial infection. Among antimicrobial coating, zinc oxide (ZnO) stands as one of the excellent materials owing to zero toxicity, high biocompatibility to human organs, good stability, high abundancy, affordability, and high photocatalytic performance to kill various infectious pathogens. Therefore, this review provides the latest research progress on advanced applications of ZnO nanostructure-based antibacterial coatings for medical devices, biomedical applications, and health care facilities. Finally, future challenges and clinical practices of ZnO-based antibacterial coating are addressed.

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Flexible Antibacterial Coatings

Cited by 23 publications

References 46 publications

Antimicrobial Nanostructured Coatings: A Gas Phase Deposition and Magnetron Sputtering Perspective

Antimicrobial Nanostructured Coatings: A Gas Phase Deposition and Magnetron Sputtering Perspective

Functionalized Cellulose for Water Purification, Antimicrobial Applications, and Sensors

ZnO-based antimicrobial coatings for biomedical applications

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