Flexible Electrode for Rapid Glucose Detection Based on CuO Nanoflowers/Stereo‐Graphene Coated on Carbon Cloth

Abstract

Designing a highly sensitive, fast response, cheap, and flexible biosensing platform has important significance in the diagnosis of diabetes. Herein, we developed an ultra‐fast and sensitive glucose sensor based on CuO nanoflowers‐coated stereo‐graphene electrode on carbon cloth. The three‐dimensional graphene (3DG) nanostructures were established on the carbon cloth (CC) by radio frequency plasma enhanced chemical vapor deposition (RF‐PECVD), and CuO nanoflowers subsequently obtained via chemical deposition. The prepared CuO@3DG@CC electrode with self‐assembled structures provided abundant ion diffusion channels, large specific surface area and high conductivity, which shows an ultrasensitive current response to glucose. The detection limit of the sensor is as low as 0.068 μM and the response efficiency is as fast as 0.5 s. The electrode has two linear ranges with 0.5–115.5 μM and 165.5–1165.5 μM and has a strong anti‐interference ability and shows an excellent stability. This kind of flexible enzyme‐free glucose sensor has been successfully applied to the detection of glucose in actual serum samples and shows a good accuracy, which is likely be applied to the medical testing field and the commercial production and has potential to further applied in wearable sensors.

Enantioselective SN1-type Reaction via Electrochemically Generated Chiral α-Imino Carbocation Intermediate

“…Enantioselective C-H hydroxylation with water as the terminal oxygen donors represents an ideal process in terms of reaction economy. There are reports on hydroxylation at the α-postion achieved by several oxygen sources 33 , however, such process with water has not been achieved in asymmetric catalysis. In our case, water can be successfully applied in this electrochemical SN1-type process to give the expected chiral tertiary alcohols with 35-54% yield and up to 84% ee (3a-i) with benzoic acid as an additive.…”