Flexible End2End Workflow Automation of Hit-Discovery Research

Holzmüller-Laue, Silke; Göde, Bernd; Thurow, Kerstin

doi:10.1177/2211068213520402

Cited by 8 publications

(7 citation statements)

References 10 publications

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“…For the HWMS the generic approach represents an open communication approach for arbitrary process‐execution information up to the end‐to‐end workflow. Celisca has investigated this approach in , . Generic LIMS do not only save the open hierarchical process‐data mapping but also the demand‐oriented management of master data, which involve the properties of the automation systems.…”

Section: Hierarchical Workflow Management Systemmentioning

confidence: 99%

Workflow Management System for the Integration of Mobile Robots in Future Labs of Life Sciences

Neubert

Göde

et al. 2019

Chemie Ingenieur Technik

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A present goal of life science automation is to network the wide range of automation systems distributed in laboratory buildings to control whole process chains. This work pursues the approach of combining mobile robots, human operators and established automation solutions in complex life science workflows. To achieve a higher level of automation, mobile robots assume the transportation tasks between the existing automation islands. A hierarchical workflow management system allows the planning, scheduling and autonomous execution of workflows in comprehensive laboratory infrastructures.

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Section: Hierarchical Workflow Management Systemmentioning

confidence: 99%

Workflow Management System for the Integration of Mobile Robots in Future Labs of Life Sciences

Neubert

Göde

et al. 2019

Chemie Ingenieur Technik

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“…The already treated investigations of BPMS solutions 1-3 (in Fig. 2) were extensively discussed by Holzmüller-Laue et al 18,21,22,25 The approach of Holzmüller-Laue et al used a centralized BPMS-controlled structure, which controls all subsystems and appropriately requires an overall systems integration in BPMSs (see Fig. 3, concept 1).…”

Section: Experiences With Bpm In Hierarchically Structured Laboratorymentioning

confidence: 99%

“…As presented in the introduced research work, the implementation of BPMSs at the workflow automation level opens new beneficial possibilities in laboratory automation. Various processed applications were already performed, for example, drug screening in an environment with connected automation islands, as described by Holzmüller-Laue et al 25 Thereby, the BPMN overall process modeling took place considering subsystems executed by PCSs. An unbound structure of the subsystems was assumed.…”

Section: Necessity To Comply With Hierarchical Structures Of Laboratomentioning

confidence: 99%

Potential of Laboratory Execution Systems (LESs) to Simplify the Application of Business Process Management Systems (BPMSs) in Laboratory Automation

Neubert

Göde

et al. 2017

SLAS Technology

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Modern business process management (BPM) is increasingly interesting for laboratory automation. End-to-end workflow automation and improved top-level systems integration for information technology (IT) and automation systems are especially prominent objectives. With the ISO Standard Business Process Model and Notation (BPMN) 2.X, a system-independent and interdisciplinary accepted graphical process control notation is provided, allowing process analysis, while also being executable. The transfer of BPM solutions to structured laboratory automation places novel demands, for example, concerning the real-time-critical process and systems integration. The article discusses the potential of laboratory execution systems (LESs) for an easier implementation of the business process management system (BPMS) in hierarchical laboratory automation. In particular, complex application scenarios, including long process chains based on, for example, several distributed automation islands and mobile laboratory robots for a material transport, are difficult to handle in BPMSs. The presented approach deals with the displacement of workflow control tasks into life science specialized LESs, the reduction of numerous different interfaces between BPMSs and subsystems, and the simplification of complex process modelings. Thus, the integration effort for complex laboratory workflows can be significantly reduced for strictly structured automation solutions. An example application, consisting of a mixture of manual and automated subprocesses, is demonstrated by the presented BPMS-LES approach.

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“…Modern process-driven applications cover the advanced workflow process automation, systems integration in hybrid and heterogeneous information technology (IT) environments, and improved process-guided support of human tasks and automated documentation. Here, new methods and standards of business process management allow new automation approaches in laboratories, of which challenges, concepts, and proof of principles are introduced in Holzmüller-Laue et al 1 The conceptual framework is a model-driven development with the standardized graphical process notation BPMN 2.0 (OMG–Standard Business Process Model and Notation 2 ), which is directly executable by a process engine on the workflow automation level. The process engine calls activities according to their ordering in the process model and taking into account process states.…”

Section: Introductionmentioning

confidence: 99%

“…Suitable interfaces, standards for protocols, and data formats are required to do this. In extension to Holzmüller-Laue et al, 1 we discuss here aspects of the implementation and systems integration within a composite application. The focus of this article is on the synergy of business process management systems and generic process documentation platforms using an example of a laboratory information management system (LIMS).…”

Section: Introductionmentioning

confidence: 99%