“…The research on wearable sensors has achieved significant advancements in the field of human sweat-based health monitoring. − Currently, wearable sensors based on various detection methods, such as colorimetric, fluorescence, electrochemical, and surface-enhanced Raman scattering (SERS) techniques, have been developed for instant, continuous, noninvasive, and accurate detection of analytes in biological fluids. − By harnessing the noninvasive sweat transmission method, these sensors can reflect the physiological and pathological conditions of the human body. For instance, colorimetric and fluorescence methods, when combined with smartphones and applications, enable in situ sensing of various sweat components (lactate, glucose, chloride, and pH). , Wireless wearable electrochemical monitoring platforms have been developed for the long-term continuous analysis of multiple sweat biomarkers such as lactate, pH, vitamin, and tyrosine, which provide insights into the metabolic stressors and physiological responses to exercise. − However, colorimetric and fluorescence techniques exhibit significant limitations in long-term continuous monitoring, , while electrochemical techniques not only require intricate electrode design and complex circuitry , but also exhibit less composition information and poor anti-interference ability. , On the contrary, SERS can provide plentiful compositional information by virtue of the inherent molecular fingerprints of analytes and is basically insusceptible to external factors. , However, its application in human sensing has been less studied.…”