“…However, it remains challenging to improve the sensors performance from multiple aspects simultaneously and realize the on-demand design of mechanical force sensors for specific application scenarios. As shown in Figure 1 , many applications in healthcare and diagnosis are opened up by developments of flexible mechanical force sensors, including pulse wave [ 110 , 111 , 112 , 113 , 114 , 115 ] and muscle softness detection [ 116 ], ICP and IOP measurement [ 117 , 118 , 119 ], throat and cardiac activity monitoring [ 55 , 120 ], abdomen and pulse diagnoses [ 121 , 122 ], as well as force sensing in orthotics [ 123 , 124 ], orthodontics [ 125 ] and skin-prosthesis interface [ 64 ]. While many excellent reviews of flexible pressure sensors can be found in the literature [ 126 , 127 , 128 , 129 , 130 , 131 , 132 , 133 , 134 , 135 , 136 , 137 , 138 , 139 , 140 , 141 , 142 ], they focus mainly on the working mechanisms, material selections and device performances.…”