2010
DOI: 10.1021/ac1027066
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Flexographically Printed Fluidic Structures in Paper

Abstract: This Technical Note demonstrates a simple method based on flexographic printing of polystyrene to form liquid guiding boundaries and layers on paper substrates. The method allows formation of hydrophobic barrier structures that partially or completely penetrate through the substrate. This unique property enables one to form very thin fluidic channels on paper, leading to reduced sample volumes required in point-of-care diagnostic devices. The described method is compatible with roll-to-roll flexography units f… Show more

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Cited by 323 publications
(210 citation statements)
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“…These devices use hydrophobic barriers patterned on hydrophilic paper by photolithography, 7 by printing with PDMS 8 or dissolved polystyrene, 9 or by solid wax applied by a commercial printer 10,11 to create microfluidic channels that guide the transport of fluids into discreet test zones. It is also possible to extend the topology of the microfluidic channels into the third dimension by stacking 12 analyze the image and transmit the results back to the user by text message.…”
Section: Micro-paper-based Analytical Devices (µPads)mentioning
confidence: 99%
“…These devices use hydrophobic barriers patterned on hydrophilic paper by photolithography, 7 by printing with PDMS 8 or dissolved polystyrene, 9 or by solid wax applied by a commercial printer 10,11 to create microfluidic channels that guide the transport of fluids into discreet test zones. It is also possible to extend the topology of the microfluidic channels into the third dimension by stacking 12 analyze the image and transmit the results back to the user by text message.…”
Section: Micro-paper-based Analytical Devices (µPads)mentioning
confidence: 99%
“…1,2 Recent developments incorporate hydrophobic barriers, 3,4 microfluidic channels 5 and stacking layers for sensing purposes. 6 Among other characteristics, paper is a low cost material, readily available, and is also flexible.…”
mentioning
confidence: 99%
“…width and length) of the device. The conventional methods used for creating hydrophobic barriers are inkjet printing [17][18][19], wax printing [20,21], flexographic printing [22], photolithography [23], wax dipping [24], plasma treatment [19,25], screenprinting of poly(dimethylsiloxane) (PDMS) [15], lacquer spraying [26] and using a permanent marker [27]. The details of these fabrication methods have been studied comprehensively by several researchers [11,28,29].…”
Section: Fabrication Techniquesmentioning
confidence: 99%