Ship cabins are places for the crew to be on duty and have a rest. The convention sets a high limitation for noises of ship cabins. This paper combined finite element method with boundary element method to study and improve the noise of ship cabins. Firstly, this paper established the finite element model of a ship cabin, computed structural response, took the structural response as boundary condition and input it into acoustic software to couple with boundary element model, realize the computation of vibro-acoustic coupling and obtain sound pressure response. Then, the numerically computational sound pressure was compared with experimental results, and a good consistency was presented. It showed that the vibro-acoustic coupling model of the ship cabin in this paper was effective. In addition, this paper also computed the noise contribution of cabin panels to observation points and obtained panels which had a serious contribution to cabin noises. Finally, this paper applied laminated plate structure to these panels and recomputed cabin noises to compare with the original structure. Results showed that peak noises of field points were obviously improved, which ensured that the noise level of ship cabins satisfied the corresponding requirements of the convention.