Flow behaviour in an asymmetric compliant experimental model for abdominal aortic aneurysm

Deplano, Valérie; Knapp, Yannick; Bertrand, Éric; Gaillard, Emmanuel

doi:10.1016/j.jbiomech.2006.11.017

Cited by 61 publications

(53 citation statements)

References 12 publications

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“…This paper presents a study of pulsatile (physiological) flow through an axisymmetric model aneurysm with a wall that is described by a Gaussian function. In doing so, we follow, to a certain extent, the 'simplified approach' of the work by Taylor & Yamaguchi (1994), Finol, Keyhani & Amon (2002), Yip & Yu (2002), Salsac, Sparks & Lasheras (2004), Deplano et al (2007) and Sheard (2009). Regarding the assumption of an axisymmetric geometry, it may be added that it has been observed that aneurysms tend to be symmetric during the early stages of the disease, only becoming non-axisymmetric during the later stages, as reported in Salsac (2005).…”

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confidence: 99%

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Dynamics of pulsatile flow through model abdominal aortic aneurysms

2014

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To contribute to the understanding of flow phenomena in abdominal aortic aneurysms, numerical computations of pulsatile flows through aneurysm models and a stability analysis of these flows were carried out. The volume flow rate waveforms into the aneurysms were based on measurements of these waveforms, under rest and exercise conditions, of patients suffering abdominal aortic aneurysms. The Reynolds number and Womersley number, the dimensionless quantities that characterize the flow, were varied within the physiologically relevant range, and the two geometric quantities that characterize the model aneurysm were varied to assess the influence of the length and maximal diameter of an aneurysm on the details of the flow. The computed flow phenomena and the induced wall shear stress distributions agree well with what was found in PIV measurements by Salsac et al. (J. Fluid Mech., vol. 560, 2006, pp. 19-51). The results suggest that long aneurysms are less pathological than short ones, and that patients with an abdominal aortic aneurysm are better to avoid physical exercise. The pulsatile flows were found to be unstable to three-dimensional disturbances if the aneurysm was sufficiently localized or had a sufficiently large maximal diameter, even for flow conditions during rest. The abdominal aortic aneurysm can be viewed as acting like a 'wavemaker' that induces disturbed flow conditions in healthy segments of the arterial system far downstream of the aneurysm; this may be related to the fact that one-fifth of the larger abdominal aortic aneurysms are found to extend into the common iliac arteries. Finally, we report a remarkable sensitivity of the wall shear stress distribution and the growth rate of three-dimensional disturbances to small details of the aneurysm geometry near the proximal end. These findings suggest that a sensitivity analysis is appropriate when a patient-specific computational study is carried out to obtain a quantitative description of the wall shear stress distribution.

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confidence: 99%

“…Here, the articles by Egelhoff et al (1999), Taylor, Hughes & Zarins (1999), Deplano et al (2007), Les et al (2010) and Suh et al (2011) should be mentioned. It has been hypothesized that prolonged physical exercise may eventually slow the growth of aneurysms, but supporting arguments are indecisive.…”

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confidence: 99%

Dynamics of pulsatile flow through model abdominal aortic aneurysms

2014

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“…Understanding the role of fluid dynamics in AAA, including the velocity, vortex, shear stress, and pressure evolution, can lead to improved medical care and rupture diagnosis since the internal mechanical forces are maintained by the dynamic action of the blood flowing in the AAAs [1]. This study provides a numerical investigation of the fluid-structure interaction in abdominal aortic aneurysm models as a means of assessing rupture potential non-invasively.…”

Section: Discussionmentioning

confidence: 99%

“…Abdominal aortic aneurysm (AAA) is a prevalent disease that is characterized by a localized, permanent dilatation of the infrarenal abdominal aorta, similar to a balloon [1]. AAAs pose a health risk due to potential thrombus formation and dissection; however, most importantly, if an AAA is left untreated, the aneurysm will continue to steadily grow until it ruptures [2].…”

Section: Introductionmentioning

confidence: 99%

A numerical study of fluid-structure coupled effect of abdominal aortic aneurysm

Cong

Li-ya

Liu

2015

BME

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Abstract. Three numerical models of an abdominal aortic aneurysm (AAA) with different geometric parameters are established in order to examine the coupled effect of the fluid-structure of AAA. The study is focused on examining the roles of the dilatation parameter and the aspect ratio of an AAA in the flow dynamic within a pulse period. The numerical results demonstrate that the vortex dominates the dynamic flow behavior within an AAA. During a pressure impulse cycle, an AAA is influenced by the entirety of the vortex, from its generation to its subsequent disappearance. As an indirect effect of the vortex dynamic acting on vessels, a series of alternate impulse responses of the wall shear stress (WSS) is generated in an AAA as eddies induced by the vortex move along the axis of the vessels, and the strength of the responses is proportional to the strength of the eddies. The alternated impulse of WSS may be one of the main influencing factors on AAA rupture. The results of this study aided in understanding the mechanisms underlying the evolutionary processes of AAAs.

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“…On the other hand, an aneurysm is illustrated as circumscribed dilation of an artery emerging from a procured or congenital debility of the arterial wall. Moreover, an abdominal aortic aneurysm (AAA) is observed when an abnormal ballooning occurs in the abdominal aorta (Deplano et al, 2007). Atherosclerotic lesions essentially are seen in arterial segments with high curvature or bifurcations and junctions initiating notable alterations in flow structure (Berger and Jou, 2000).…”

Section: Introductionmentioning

confidence: 99%

Pulsatile Non-Newtonian Fluid Flows in a Model Aneurysm with Oscillating Wall

2017

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This research presents a numerical simulation of an unsteady two-dimensional channel flow of Newtonian and some non-Newtonian fluids using the finite-volume method. The walls of the geometry oscillate sinusoidally with time. We have used the Cartesian curvilinear coordinates to handle complex geometries, i.e., arterial stents and bulges and the governing Navier-Stokes equations have been modified accordingly. Physiological pulsatile flow has been used at the inlet to characterize four different non-Newtonian models, i.e., the (i) Carreau, (ii) Cross, (iii) Modified Casson, and (iv) Quemada. We have presented the numerical results in terms of wall shear stress (WSS), pressure distribution as well as the streamlines and discussed the hemodynamic behaviors for laminar and laminar to turbulent transitional flow conditions. An increase of wall shear stress and a decrease in wall pressure are significantly observed at the stenosis throat for high Reynolds number and highly stenosed arteries. Likewise, the flow recirculation also increases if the narrowing level and the Reynolds number increases in the dilated region which eventually leads the stream to experience a transition to turbulence at Re = 750. The results for the fluid flow through an aneurysm just after a stenosis with oscillating wall are novel in the literature.

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Flow behaviour in an asymmetric compliant experimental model for abdominal aortic aneurysm

Cited by 61 publications

References 12 publications

Dynamics of pulsatile flow through model abdominal aortic aneurysms

Dynamics of pulsatile flow through model abdominal aortic aneurysms

A numerical study of fluid-structure coupled effect of abdominal aortic aneurysm

Pulsatile Non-Newtonian Fluid Flows in a Model Aneurysm with Oscillating Wall

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