To investigate the effect of blade wrap angle on the hydrodynamic radial force of a single blade centrifugal pump, numerical simulation is conducted on the pumps with different blade wrap angles. The effect of the wrap angle on the external characteristics and the radial force of a single blade centrifugal pump was analyzed according to the simulation result. It is found that, with the increase of the blade wrap angle, the head and efficiency of the single blade centrifugal pump are improved, the H-Q curve becomes steeper, and the efficiency also increased gradually, while the high-efficiency area is narrowed. The blade wrap angle has a great effect on the radial force of the single blade centrifugal pump. When the blade wrap angle is less than 360°, the horizontal component of the radial force is negative and the value is reduced with the increase of the wrap angle of the blade. When the wrap angle is larger than 360°, the horizontal component of the radial force is positive and the value increases with the increase of the wrap angle. Under part-loading conditions, the radial force of the single blade pump is significantly reduced with the increase of the blade wrap angle. When the wrap angle is smaller than 360°, the radial force decreases with the flow rate increase. In the condition that the wrap angle is larger than 360°, the radial force increases with the flow rate increase.