2006
DOI: 10.1016/j.jacc.2005.05.100
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Flow-Dependent Changes in Doppler-Derived Aortic Valve Effective Orifice Area Are Real and Not Due to Artifact

Abstract: The flow-dependent changes in EOA(Dop) are not artifacts but represent real changes in EOA attributable either to unsteady effects at low flow rates and/or to changes in valve leaflet opening. Such changes in EOA(Dop) can be relied on for clinical judgment making.

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Cited by 48 publications
(18 citation statements)
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“…In patients with impaired left ventricular function resulting in decreased validity of pressure gradient measurements, non-invasive determination of the degree of aortic valvular stenosis according to the continuity equation may be superior, especially since planimetric measurement of aortic valvular areas is affected by actual transvalvular flow [24][25][26]. Transesophageal echocardiography provides a good acoustic window and thus superior image resolution which allows accurate direct measurement in many patients by multiplane [27,28] and three-dimensional approach [29,30].…”
Section: Discussionmentioning
confidence: 99%
“…In patients with impaired left ventricular function resulting in decreased validity of pressure gradient measurements, non-invasive determination of the degree of aortic valvular stenosis according to the continuity equation may be superior, especially since planimetric measurement of aortic valvular areas is affected by actual transvalvular flow [24][25][26]. Transesophageal echocardiography provides a good acoustic window and thus superior image resolution which allows accurate direct measurement in many patients by multiplane [27,28] and three-dimensional approach [29,30].…”
Section: Discussionmentioning
confidence: 99%
“…As for the pressure recovery, a remark should be made on these modelling results in relation to the physiological situation. Although the EOA dop is often assumed independent to flow, in-vitro experiments have been defined with flow through circular orifice shapes demonstrating flowdependence [7], attributed to either a change of the jet profile [17] or an actual change in the GOA like found in the modelling results. Note that three-dimensional modelling would allow for a similar analysis on non-circular or eccentric orifices.…”
Section: Flow Dependence Of Eoa Dopmentioning
confidence: 99%
“…Flow-dependent changes in AVA are real. An in-vitro study (14) using particle image velocimetry (PIV) in bioprosthetic valves showed good agreement with Doppler (DOP)-derived effective orifice area (EOA) (r 2 ϭ 0.94). When stroke volume was increased from 20 ml to 70 ml, there were substantial and similar increases by both methods: ϩ52% for EOA DOP versus ϩ63% for EOA PIV.…”
Section: Valve Calcification As Marker For Severity Is Inaccuratementioning
confidence: 93%