Flow-Diverter Silk Stent for the Treatment of Intracranial Aneurysms: 1-year Follow-Up in a Multicenter Study

Berge, Jérôme; Biondi, Alessandra; Machi, Paolo; Brunel, H.; Piérot, Laurent; Gabrillargues, Jean; Kadziolka, K.; Barreau, Xavier; Dousset, V.; Bonafé, Alain

doi:10.3174/ajnr.a2907

Cited by 180 publications

(170 citation statements)

References 22 publications

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“…However unknown the mechanism leading to these hemorrhages remains, some factors such as hemorrhagic transformation and use of anti-platelet are alleged as guilty culprits (16)(17)(18). No intraparenchymal hemorrhages were observed in our study although the rates of the hemorrhages were reported to range between 0% and 10% in several studies (16)(17)(18).…”

Section: Discussioncontrasting

confidence: 52%

The Efficacy of Flow Diverter Stents in the Treatment of Wide-Necked Intracranial Aneurysms

Özdemır

Arslan²,

Duman

et al. 2017

Iran J Radiol

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Background: To present our findings obtained from the treatment of wide-necked intracranial aneurysms with flow diverter stents. Patients and Methods: Intracranial aneurysms were determined in 19 patients (14 females, 5 males; mean age, 56.6 years) between May 2011 and June 2014, and the patients were treated using flow diverter stents. A total of 28 flow diverter stents, including 9 Silk and 19 Pipeline stents were used. Occlusion rates evaluated with computed tomography at the end of month 6 and digital subtraction angiography after one year, intraoperative success, morbidity and mortality rates were determined. Results: A total of 20 endovascular interventions, including two interventions in two different aneurysms in one patient were performed in 19 patients. Flow diverter stents were successfully implemented for wide-necked aneurysms at a success rate of 100%. Coil treatment had previously been performed in four patients. Aneurysm occlusion rates were 77.2% at month 6 and 90.9% at the end of month 12. Conclusions: The use of flow diverter stents is a reliable and effective method in the treatment of wide-necked intracranial aneurysms with high aneurysm occlusion, and low morbidity and mortality rates.

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Section: Discussioncontrasting

confidence: 52%

The Efficacy of Flow Diverter Stents in the Treatment of Wide-Necked Intracranial Aneurysms

Özdemır

Arslan²,

Duman

et al. 2017

Iran J Radiol

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“…Recently, several flow-diverter stents, such as the Silk flow diverter (Balt Extrusion, Montmorency, France), have been released, and short-and midterm results have been published. [7][8][9][10][11][12][13][14][15] Notwithstanding the early promise of these devices, important shortcomings have been reported. First, delayed complications, either hemorrhagic or thromboembolic, are not uncommon; second, the flow-diverter stent tolerance might be considered poor because of the relatively high rates of intrastent stenosis and parent artery occlusion (PAO) during follow-up.…”

Section: -4mentioning

confidence: 99%

“…First, delayed complications, either hemorrhagic or thromboembolic, are not uncommon; second, the flow-diverter stent tolerance might be considered poor because of the relatively high rates of intrastent stenosis and parent artery occlusion (PAO) during follow-up. [7][8][9][10][11][12][13][14][15] To the best of our knowledge, sparse data are available about the long-term results of this technique, including stability of aneurysm occlusion and stent tolerance. These data are mandatory to define the place of flow-diverter stents in the therapeutic armamentarium of intracranial aneurysms.…”

Section: -4mentioning

confidence: 99%

“…Most stenoses were asymptomatic, but our rate is significantly superior compared with that in previous series. [7][8][9][10][11][12][13][14][15] Indeed, the incidence of intrastent stenosis was 7.8% in the Berge et al series, 10 6% in the Byrne et al series, 10 and 5% in the Murthy et al meta-analysis. 14 Nevertheless, the only series that is almost comparable with ours is that of Cohen et al, 15 which was also focused on this precise evaluation.…”

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confidence: 99%

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Silk Flow-Diverter Stent for the Treatment of Intracranial Aneurysms: A Series of 58 Patients with Emphasis on Long-Term Results

Lubicz

Elst

Collignon

et al. 2014

AJNR Am J Neuroradiol

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“…Studien zeigten sich In-Stent-Thrombosen oder -stenosen in 18 -33 % der berichteten Fälle nach 6 Monaten [7,10] …”

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3-Jahres-Follow nach Aneurysmabehandlung mit dem Silk® Flow Diverter

Ringelstein

Schlamann

Goericke

et al. 2013

Fortschr Röntgenstr

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Zusammenfassung Ziel: Flow Diverter (FD) k?nnen Aneurysmen durch eine endoluminalen Rekonstruktion des Tr?gergef??es und die Reduktion des Bluteinstroms in das Aneurysma verschlie?en. Diese Studie zeigt die interventionsassoziierte Komplikationsrate und das angiografische und klinische Outcome 3 Jahre nach der Behandlung. Material und Methoden: Wir analysierten retrospektiv 18 nicht rupturierte Aneurysmen bei 18 Patienten, die mit Silk?-FD behandelt wurden. Die Patienten erhielten eine MRT/MRA-Kontrolluntersuchung noch w?hrend des station?ren Aufenthalts und mindestens eine DSA- und/oder MRT/MRA-Verlaufskontrolle nach 6 Monaten, nach 18 Monaten und nach 3 Jahren. Die Behandlungsindikationen waren fusiforme Aneurysmen, Riesenaneurysmen oder Aneurysmarezidive. Alle Aneurysmen waren nach interdisziplin?rer Einsch?tzung mittels konventioneller Therapien nicht behandelbar. Ergebnisse: Die FD konnten bei 16/18 Patienten korrekt platziert werden. In einem Fall wurde eine zus?tzliche PTA des Stents notwendig. In einem anderen Fall hat sich der erste FD nicht entfaltet, er wurde durch einen zweiten FD komplikationslos ersetzt. Bei 3 vorbehandelten Aneurysmen konnte sofort nach Stenteinlage eine Thrombosierung des?Aneurysmas beobachtet werden. Alle anderen Aneurysmen zeigten zumindest eine Kontrastierungsverz?gerung. Im ersten Follow-up nach 6 Monaten und auch langfristig nach 3 Jahren zeigten sich 17 von 18 Aneurysmen (95?%) vollst?ndig ausgeschaltet. Die technische Komplikationsrate betrug 11,1?% (2/18). Komplikationen traten ohne klinische Relevanz bei 11,1?% (2/18) und mit schweren persisitierenden neurologischen Defiziten bei 16,6?% (3/18) der Patienten auf. 15 von 18 Patienten wiesen bei Entlassung einen Wert von 0 auf der modifizierten Rankin-Skala auf, ein Patient einen Wert von 3, zwei Patienten einen Wert von 4. Schlussfolgerung: Aneurysmabehandlungen mit dem SILK? Flow Diverter zeigen eine dauerhaft niedrige Rezidivrate. Die Komplikationsrate ist bei den komplexen Aneurysmen dieser Studie aber h?her als bei konventioneller Aneurysmabehandlung.

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Flow-Diverter Silk Stent for the Treatment of Intracranial Aneurysms: 1-year Follow-Up in a Multicenter Study

Abstract: BACKGROUND AND PURPOSE: FD stent placement is a promising therapy for challenging intracranial aneurysms. Long-term evaluations about angiographic and morphologic results are still missing. This is the aim of this multicenter series.

Cited by 180 publications

References 22 publications

The Efficacy of Flow Diverter Stents in the Treatment of Wide-Necked Intracranial Aneurysms

The Efficacy of Flow Diverter Stents in the Treatment of Wide-Necked Intracranial Aneurysms

Silk Flow-Diverter Stent for the Treatment of Intracranial Aneurysms: A Series of 58 Patients with Emphasis on Long-Term Results

3-Jahres-Follow nach Aneurysmabehandlung mit dem Silk® Flow Diverter

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