Flow dynamics of vitreous humour during saccadic eye movements

Abstract

In this work, we reveal the flow dynamics of Vitreous Humour (VH) gel and liquid phases during saccadic movements of the eye, considering the biofluids viscoelastic character as well as realistic eye chamber geometry and taking into account the saccade profile. We quantify the differences in the flow dynamics

Iris Fluttering Detected by Anterior Segment Optical Coherence Tomography in Eyes with Intrascleral Fixation of Intraocular Lens

“…The absence of the vitreous gel after vitrectomy is believed to enhance the ow of vitreous humor into the anterior chamber during eye movements. Silva and associates 13 reported that computational uid dynamics of vitreous humor during saccadic eye movements was different for the gel phase in the vitreous cavity than that with the liquid phase because the inertial effects were more signi cant with the liquid vitreous. In contrast, the shear stress produced by the gel phase of vitreous humor more than twice that of liquid phase.…”

“…In contrast, the shear stress produced by the gel phase of vitreous humor more than twice that of liquid phase. 13 After an intrascleral xation of an IOL without a lens capsular support, the height of the temporal sector of the iris increased, and the nasal sector decreased immediately after the eye moved from a temporal gaze to the primary position. The aqueous humor is more susceptible to the inertia moments than the vitreous humor during eye movements because the aqueous humor is located further from the center of the eye.…”

“…The eye is lled with uid, and saccadic eye movements and body motions cause a movement of the intraocular uids which generates shear stress on the ocular tissues in contact with the uids. 13 The movement of the aqueous humor and vitreous humor during eye movements have been analyzed with a computational model because it is di cult to observe and measure them in situ in alive human eyes. [13][14][15][16][17] The anterior segment optical coherence tomographic (AS-OCT) devices were designed to record crosssectional images of the anterior segment of the eye.…”

“…13 The movement of the aqueous humor and vitreous humor during eye movements have been analyzed with a computational model because it is di cult to observe and measure them in situ in alive human eyes. [13][14][15][16][17] The anterior segment optical coherence tomographic (AS-OCT) devices were designed to record crosssectional images of the anterior segment of the eye. 18,19 Swept source AS-OCT uses a longer wavelength light source of 1310 nm which enables the scanning of the anterior and posterior surface of an IOL.…”

Effects of Flow Hydrodynamics and Eye Movements on Intraocular Drug Clearance

“…In recent years, research has been reported [15,17,[22][23][24][25][26][27] to study the effects of saccades on the convective-diffusive behaviour of a drug via IVT delivery. Saccadic eye movements are ballistic movements produced by both eyes, and help orient the line of sight when fixating on an object [28,29]. The characteristics of saccades include a very high initial acceleration, a weaker deceleration, and a peak angular velocity associated with the saccadic amplitude [24].…”