Flow Injection Chemiluminescence Determination of Captopril with In Situ Electrogenerated Mn3+ as the Oxidant

Zheng, Xusheng; Zhang, Zhujun; Li, Baoxin

doi:10.1002/1521-4109(200108)13:12<1046::aid-elan1046>3.0.co;2-5

Cited by 33 publications

(5 citation statements)

References 35 publications

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“…15 Therefore, the determination of captopril is important from a physiological point of view as well as for the purposes of quality control. Several methods have already been reported for the determination of captopril in pharmaceutical formulations and clinical samples, including high performance liquid chromatography, [16][17][18][19][20][21][22] gas chromatography, 23,24 photometry, 25 spectrophotometry, [26][27][28][29][30][31] fluorimetry, 32,33 radiochemical, 34 FT-Raman spectroscopy, 35 capillary electrophoresis, [36][37][38] chemiluminescence [39][40][41][42] and electrochemical methods. [43][44][45][46] Here, we have demonstrated the electrocatalytic potential of Mn-nanoparticles decorated organo-functionalized nanosized SiO 2 -Al 2 O 3 mixed-oxide as a mediator in catalytic determination of captopril.…”

Section: Introductionmentioning

confidence: 99%

Characterization of Mn-nanoparticles decorated organo-functionalized SiO2–Al2O3 mixed-oxide as a novel electrochemical sensor: application for the voltammetric determination of captopril

et al. 2011

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In this work a new sensor in nano size containing Mn-nanoparticles decorated organo-functionalized nanosized SiO 2 -Al 2 O 3 mixed-oxide support was developed as a new electrocatalysis for oxidation of organic compounds such as captopril. SiO 2 -Al 2 O 3 mixed-oxide were functionalized with Schiff base ligand and thereatfer, in the next step, Mn-nanoparticles were prepared over the organofunctionalized SiO 2 -Al 2 O 3 mixed-oxide. The synthesized materials were characterized with different methods such as FT-IR spectroscopy, UV-vis, CHN elemental analysis, TEM, ICP-OES, cyclic voltammetry, and electrochemical impedance spectroscopy. Under the optimum conditions (pH 7.0) in cyclic voltammetry, the oxidation of the captopril was occurred at a potential about 650 mV at a surface of the modified electrode. Linear sweep voltammetry exhibited two wide linear dynamic ranges of 0.30-5.0 and 5.0-340 mmol L À1 captopril. The detection limit was found to be 0.095 mmol L À1 captopril. The kinetic parameters such as electron transfer coefficient and catalytic reaction rate constant were also determined. Finally, the modified electrode used as a novel electrochemical sensor for the determination of captopril in real samples such as pharmaceutical, patient and safe human urine.

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Section: Introductionmentioning

confidence: 99%

Characterization of Mn-nanoparticles decorated organo-functionalized SiO2–Al2O3 mixed-oxide as a novel electrochemical sensor: application for the voltammetric determination of captopril

et al. 2011

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“…These reactions are commonly controlled by a potentiostat or an amperometric unit [8][9][10][11], which establish potential differences or electric current flows between the electrodes of the cell, respectively, to collect the emitted light in ECL reactions, electromagnetic radiation sensors must be used. Photomultiplier tubes (PMT) are widely used as laboratory instrumentation for ECL reactions [12].…”

Section: Introductionmentioning

confidence: 99%

Portable system for photodiode-based electrochemiluminescence measurement with improved limit of detection

Carvajal

Ballesta-Claver

Martínez-Olmos

et al. 2015

Sensors and Actuators B: Chemical

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“…Different techniques have been developed in order to measure the light resulting from electroluminescence reactions. Those processes are commonly controlled by a potentiostat or an amperometric unit (Gautron et al, 1980;Zheng et al, 2001) which establish potential differences or electric current flow between the electrodes of the cell, respectively. When there are no requirements regarding the size or the power supply needed for the design, a good solution to collect the weak photons generated by the ECL reaction is the use of a photomultiplier tube (PMT) (Zhou et al, 2004).…”

Section: Introductionmentioning

confidence: 99%

Portable Instrumentation Platform for Ecl-Based Sensors and Biosensors

Palma¹,

Carvajal²,

López-Ruiz³

et al. 2011

Proceedings of the International Conference on Biomedical Electronics and Devices

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A new portable instrumentation platform for electrochemiluminescence (ECL)-based disposable sensors and biosensors is described. The reader unit consists of a potentiostat and a photodiode as light-to-current converter integrated in the same instrument. To check the performance of the instrument as sensors platform, two transduction chemistries (luminol and tris(2,2'bipyridyl)ruthenium(II)) and two widely used analytes (hydrogen peroxide and triethylamine) were selected. Additionally, different working modes have been implemented in the instrument: chronoamperometry and cyclic voltammetry. The calibration functions obtained show linear dependences with dynamic ranges from 0.01 to 0.07 mg•l-1 for H 2 O 2 , 0.05-10.0 mg•l-1 for triethylamine with detection limits of 0.01 mg•l-1 for H 2 O 2 and 0.03 mg•l-1 for triethylamine and a sensor-to-sensor reproducibility (relative standard deviation RSD) around 8.2 % and 3.1 %, respectively at the medium level of the range.

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Flow Injection Chemiluminescence Determination of Captopril with In Situ Electrogenerated Mn3+ as the Oxidant

Cited by 33 publications

References 35 publications

Characterization of Mn-nanoparticles decorated organo-functionalized SiO2–Al2O3 mixed-oxide as a novel electrochemical sensor: application for the voltammetric determination of captopril

Characterization of Mn-nanoparticles decorated organo-functionalized SiO2–Al2O3 mixed-oxide as a novel electrochemical sensor: application for the voltammetric determination of captopril

Portable system for photodiode-based electrochemiluminescence measurement with improved limit of detection

Portable Instrumentation Platform for Ecl-Based Sensors and Biosensors

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