Flow-injection solvent extraction without phase separation

Alonso, Ángel Cabo; Almendral, M.J.; Porras, M.J.; Curto, Y.

doi:10.1016/j.jpba.2006.02.011

Cited by 30 publications

(5 citation statements)

References 35 publications

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“…140 Fluorometric determination without phase separation of thiamine has been demonstrated as an alternative to HPLC. 141 Folic acid, a form of the water-soluble vitamin B 9 , is essential for numerous bodily functions and is especially important for women during pregnancy. 117 Levels of folic acid and folatebinding protein (FBP), a protein that regulates the assimilation, distribution, and retention of folates in mammalian cells, have been measured in breakfast cereals, milk, and soy-based infant formulas using SPR.…”

Section: Accurate and Highly Sensitive Analysis Of Modified Foodsmentioning

confidence: 99%

Optofluidic opportunities in global health, food, water and energy

et al. 2012

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Optofluidics is a rapidly advancing field that utilizes the integration of optics and microfluidics to provide a number of novel functionalities in microsystems. In this review, we discuss how this approach can potentially be applied to address some of the greatest challenges facing both the developing and developed world, including healthcare, food shortages, malnutrition, water purification, and energy. While medical diagnostics has received most of the attention to date, here we show that some other areas can also potentially benefit from optofluidic technology. Whenever possible we briefly describe how microsystems are currently used to address these problems and then explain why and how optofluidics can provide better solutions. The focus of the article is on the applications of optofluidic techniques in low-resource settings, but we also emphasize that some of these techniques, such as those related to food production, food safety assessment, nutrition monitoring, and energy production, could be very useful in well-developed areas as well.

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Section: Accurate and Highly Sensitive Analysis Of Modified Foodsmentioning

confidence: 99%

Optofluidic opportunities in global health, food, water and energy

et al. 2012

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“…38 These advantages are expected to greatly enhance when continuous liquid-liquid microextraction (LLME) is coupled to FIA. [39][40][41][42][43] Sequential injection analysis (SI) as a family of FIA techniques is based on the same principles: sample (and reagent) injection, controlled dispersion, and reproducible timing. However, in the SI mode, sample and reagent zones are sequentially stacked upstream from the injection valve, and subsequently mixed by reversing of the flow.…”

Section: Introductionmentioning

confidence: 99%

On-line Flow-injection Liquid-phase Microextraction and Spectrophotometric Determination of Traces of Copper(II) with Trithia-9-crown-3 as Complexing Agent

2013

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A novel on-line flow-injection liquid-phase microextraction (FI-LPME) and spectrophotometric determination of the Cu 2+ ion using trithia-9-crown-3 (TT9C3) as a sensitive and selective charge transfer complexing agent was developed. After phase segmentation by pulsating motions of a peristaltic pump, the phase separation takes place by the aid of gravitation forces. The optimum values of the pH (= 5 of phosphate buffer) and ionic strength (5 mM Na2SO4) of the solution, amount of ligand (2.0 × 10 -3 mol L -1 ), nature of the counter ion (10 mM SDS), volume of the organic solvent (150 μL), coil length (3 m) and extraction time (2 min) for an efficient extraction were determined. The calibration curve was found to be linear over a concentration range of 0.008 -4.2 μg mL -1 (R 2 = 0.9985) with a limit of detection of 0.37 ng mL -1 . The enrichment factor and relative standard deviation (n = 7) were 16 and 5.7%, respectively. Finally, the proposed method was applied to the determination of copper(II) as an impurity in the several commercial metallic salts.

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“…Since the rst report on ow injection-liquid-liquid extraction (FI-LLE) by Karlberg and Thelander, 23 an extensive amount of research work has been directed towards establishing different types of segmenters, extraction coils, separators, as main components of the FI-LLE manifold, as well as its automation using microcontrollers and relative controlling soware. [24][25][26][27][28][29] In 1988 Valcarcel and et al reported a novel strategy for liquid-liquid extraction in continuous-ow systems without phase separation, in which a single segment of organic solvent interacts with an aqueous sample for separation purposes while none of the typical components for on-line extraction are incorporated. [30][31][32][33] In the present study, we employed a similar strategy to our previous work 34 in order to develop another ow-injection liquid-liquid microextraction (FI-LLME) method for the selective uorimetric determination of CL-15 explosive.…”

Section: Introductionmentioning

confidence: 99%