Flow mediated dilatation of Taiwanese women with normal singleton pregnancies

Hou, Wen-Chien; Chen, Jui-Yu; Huang, Hsin-Yi; Sun, Yiting; Su, Her-Young; Chang, Tung-Yao

doi:10.1016/j.tjog.2018.08.012

Cited by 5 publications

(3 citation statements)

References 14 publications

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“…There are studies reporting that brachial artery FMD increases with gestational age. 26,27 Some studies also report that FMD increases in the first two trimesters and decreases in the last trimester. 28 On the contrary, there are publications reporting that there is a decrease with the gestational age.…”

Section: Discussionmentioning

confidence: 99%

“…In obese pregnant women, it decreased from the first trimester (11—14 weeks) to the second trimester (24–28 weeks), and it increased toward the third trimester (37–40 weeks) (17.4%, 15.3%, and 21.2%, respectively). There are studies reporting that brachial artery FMD increases with gestational age 26,27 . Some studies also report that FMD increases in the first two trimesters and decreases in the last trimester 28 .…”

Section: Discussionmentioning

confidence: 99%

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Comparison of brachial artery flow‐mediated dilatation, uterine artery Doppler, and umbilical artery Doppler measurements in obese and normal pregnant women

Aksin

Andan

Tunç

et al. 2021

J of Obstet and Gynaecol

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Objective In this study, we aimed to compare vascular function at trimesters 1, 2, and 3 between obese and normal pregnant women through brachial artery flow‐mediated dilatation (FMD), uterine artery Doppler, and umbilical artery Doppler measurements. Methods Pregnant women between the ages of 18 and 40 who presented to our clinic were included. Brachial artery FMD, uterine and umbilical artery Doppler, and clinical parameters of 40 obese pregnant women from each trimester between 11 and 14 weeks, 24 and 28 weeks, 37 and 40 weeks and control pregnant group in the same number and gestational week were examined. Results In all three trimesters, the FMD value was lower in obese pregnant women compared to normal women with adequate weight (p < 0.001). In obese pregnant women, lower FMD values were observed in the second trimester compared to other trimesters (p = 0.011) Cut‐off value of FMD below 14.35 in obese pregnant women was found to be associated with gestational diabetes mellitus. Uterine artery Doppler in obese pregnant women started to increase from the second trimester compared to normal women with adequate weight. Conclusion Obese pregnant women have endovascular dysfunction compared to normal pregnant women and this becomes evident from the second trimester.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Comparison of brachial artery flow‐mediated dilatation, uterine artery Doppler, and umbilical artery Doppler measurements in obese and normal pregnant women

Aksin

Andan

Tunç

et al. 2021

J of Obstet and Gynaecol

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“…The metabolic environment created by obesity disrupts placental development and causes deterioration in fetal circulation. Obesity-related systemic inflammation and insulin resistance reduce cytotrophoblast invasion and placental nitric oxide formation, resulting in placental hypoxia [18]. The presence of vascular villous lesions in healthy pregnant women without hypertension and diabetes shows that obesity is an independent risk factor with the inflammatory process created by itself [19].…”

Section: Parametersmentioning

confidence: 99%

Fetal Epicardial Fat Thickness in Obese Pregnant Women: Its Effect on Fetal Cardiac Function and Neonatal Outcomes

Doğru,

Akkuş,

Metin

et al. 2024

Z Geburtshilfe Neonatol

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Objective This study aimed to evaluate fetal epicardial fat thickness (EFT) together with fetal myocardial performance index (MPI) and its effects on neonatal outcomes in obese pregnant women. Materials and methods A total of 102 pregnant women, 51 obese and 51 of normal weight, were included in this prospective study. Fetal EFT, and MPI measurements were performed for all patients. Results Fetal EFT and Mod-MPI showed a statistically significant difference between obese pregnant women and the control group (p=0.0001, p=0.001). The optimal fetal EFT predictive cut-off value for the 5th-minute APGAR score below 7 was 1.22 mm, with a sensitivity of 86.96% and a specificity of 54.43% (p=0.001). Conclusion Fetal EFT and mod-MPI were higher in obese pregnant women. It is encouraging that fetal EFT predicts low APGAR, but more important information can be obtained if postnatal follow-up of these cardiac changes caused by obesity can be performed.

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Myosin light chain kinase inhibitor ML7 improves vascular endothelial dysfunction and permeability via the mitogen-activated protein kinase pathway in a rabbit model of atherosclerosis

Ding

et al. 2020

Biomedicine & Pharmacotherapy

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Flow mediated dilatation of Taiwanese women with normal singleton pregnancies

Cited by 5 publications

References 14 publications

Comparison of brachial artery flow‐mediated dilatation, uterine artery Doppler, and umbilical artery Doppler measurements in obese and normal pregnant women

Comparison of brachial artery flow‐mediated dilatation, uterine artery Doppler, and umbilical artery Doppler measurements in obese and normal pregnant women

Fetal Epicardial Fat Thickness in Obese Pregnant Women: Its Effect on Fetal Cardiac Function and Neonatal Outcomes

Myosin light chain kinase inhibitor ML7 improves vascular endothelial dysfunction and permeability via the mitogen-activated protein kinase pathway in a rabbit model of atherosclerosis

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