“…The GNM consists of a cylindrical capillary and a conical nanopore in series. The flow rate Q (m 3 /s) is readily derived in terms of the solution viscosity, η, (see ref and the Supporting Information for details) Q = normalΔ P ( 3 π 8 η ) false[ 3 L R 3 − 4 + cot nobreak.25em normalθ false( R 1 − 3 − R 2 − 3 false) false] − 1 where Δ P = P 3 – P 1 , L is the height of the solution in the cylindrical capillary, R 1 and R 2 are the small and large orifice radii of the nanopore, θ is the half-cone angle of the nanopore, and R 3 is the capillary radius.…”