The paper presents results of numerical simulations and experimental investigations of a cyclone with a square inlet and different dimensions of a vortex finder. Investigations were conducted for five, different cyclone models. The main goal of the research was to determine the influence of cyclone vortex finder geometry (diameter, length) on key parameters for a cyclone operation, such as: gas flow pattern, gas velocity and pressure distribution, pressure drop and collection efficiency. The analysis of flow pattern inside the cyclone was carried out with the use of CFD (Computational Fluid Dynamics) simulations, verified using CTA (Constant Temperature Anemometry). Similarly, pressure distributions, pressure drop and collection efficiency for cyclones were determined numerically and with measurements. The study demonstrated that dimensions of the vortex finder have a significant effect on a cyclone performance. The numerical visualisations of flow showed some unfavorable and beneficial effects and phenomena that may occur in cyclones. Moreover, the smallest pressure drop (305 Pa) was predicted for the cyclone with a maximum diameter of the vortex finder (De = 0.105 m), the largest (358 Pa) when this diameter was the smallest (De = 0.075 m). The tests did not show any significant influence of the vortex finder length on the pressure drop in a cyclone. A different tendency was observed in the case of collection efficiency. The maximum value of this parameter (89.5%) was predicted for the cyclone with the shortest vortex finder (s = 0.060 m), minimum (85.5%) when the vortex finder was the longest (s = 0.220 m). In this case, however, tests did not show a significant impact of an outlet diameter on the collection efficiency. Results and conclusions presented in this paper can be practically used for design optimization of cyclone separators, and also to select their operating parameters.