S. (2018). Flowsheet simulation of cobalt-nickel separation by solvent extraction with trihexyl(tetradecyl)phosphonium chloride. Industrial and Engineering Chemistry Research, 57(30). https://doi.org/10.ABSTRACT Solvent extraction is widely used for selective separation of metals from solutions. Ionic liquids are showing potential for this purpose. To date, little research has focused on design, operation and optimization of solvent extraction flowsheets using ionic liquids. This work addresses this gap in knowledge, aiming to support development, design and optimization of such solvent extraction processes. In this work, a general flowsheet simulation model is developed and applied for the case of cobalt-nickel separation using ionic liquid * Corresponding author, email: Hongyan.chen@manchester.ac.uk ORCID