Fluconazole-Niosome-Laden Contact Lens: A Promising Therapeutic Approach for Prolonged Ocular Delivery and Enhanced Antifungal Activity
Ghada E. Yassin,
Mai A. Amer,
Islam M. Mannaa
et al.
Abstract:Background
Traditional routes of administration of fluconazole such as eye drops have a low therapeutic efficacy due to insufficient bioavailability.
Purpose
Herein, a fluconazole noisome-laden contact lens was prepared to control and prolong the drug release and improve its bioavailability.
Methods
Two methods have been used to prepare fluconazole niosomes: solvent injection method and thin film hydra… Show more
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