We implemented a context-sensitive and prospective framework to assess the global warming potential (GWP) impacts of cool pavement strategies on specific roads for different cities. The approach incorporates several interconnections among different elements of the built environment, such as buildings and urban road segments, as well as the transportation fleet, using specific building and pavement information from an urban area. We show that increasing pavement albedo lowers urban air temperatures but can adversely affect the building energy demand in the areas with high incident radiation exposure. The heating energy savings and the radiative forcing effect improve the GWP savings in a cold and humid climate condition. The total GWP saving intensity is sensitive to the city morphology and road traffic. Our probabilistic results show that cool pavement strategies can offset 1.0-3.0% and 0.7-6.0% of the total GHG emissions of the US cities Boston and Phoenix, respectively, for a 50-year analysis period. The worldwide range of savings can be as large as 5.0 - 44.7 Gt CO2eq. A paradigm shift in pavement strategy selection is required in most of the neighborhoods.