Fluid Resuscitation Therapy for Hemorrhagic Shock

Spaniol, Joseph R.; Knight, Amanda R.; Zebley, Jessica L.; Anderson, Dawn E.; Pierce, Janet D.

doi:10.1097/01.jtn.0000292116.88270.57

Cited by 22 publications

(11 citation statements)

References 65 publications

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“…This value represents the short and shallow breaths. This allegation is reinforced by other researchers who state that when the body experiences the blood loss to reach more than 15%, then the body will experience the increase in the heart rate and the increase in the respiration rate [21]. However, the absence of the significance of the data of RR refers to thenonoptimal shock efforts.…”

Section: Resultsmentioning

confidence: 99%

Evaluation of ventilator on lung profile of piglets (Sus scrofa) in hypovolemic shock treated with hypervolemic crystalloid resuscitation

et al. 2019

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Aim: This study was conducted to assess the effect of ventilators on the lung profile of piglets in the hypovolemic shock before and after the excessive resuscitation of the crystalloid fluid. Materials and Methods: Five male piglets were used in this study as the models of shock, and there are four phases of treatment: Stabilization, shock of bleeding, normovolemic resuscitation, and hypervolemic resuscitation. The application of mechanical ventilation to patients who suspected of having lung injury may worsen the patient's conditions. The purpose of this study was to set the ventilator with the set of positive end-expiratory pressure (PEEP) of 5 cm H2O, the fraction of inspired oxygen (FiO2) of 0.5, and the inspiration: expiration (I: E) ratio of 1:2, which was applied from the stabilization phase. The shock induction was performed by removing the blood until the mean arterial pressure decreasing by 20% from the stabilization. The solution of NaCl 0.9% was used for the normovolemic and hypervolemic resuscitation. The parameter of observation consisted of extravascular lung water index (EVLWI) and pulmonary vascular permeability index (PVPI) on pulse contour cardiac output 2 and exhaled tidal volume (VTE), peak inspiratory pressure (PIP), and respiratory rate (RR) on ventilators. Results: EVLWI does not indicate pulmonary edema. A significant decrease in VTE without any significant alterations in EVLWI, PIP, and RR has indicated the shallow breathing in the shock condition. Therefore, the PVPI parameter cannot be used as a parameter for capillary permeability since its formulation does not reinforce the results of data in the shock condition. The set of the ventilator may prevent the increase of EVLWI, and the uses of ventilators do not worsen the patient's conditions during the crystalloid resuscitation. Conclusion: The use of mechanical ventilator as the support does not worsen the hypovolemic condition and is safe to use as long as the lung profile is not indicated to have lung injury.

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Section: Resultsmentioning

confidence: 99%

Evaluation of ventilator on lung profile of piglets (Sus scrofa) in hypovolemic shock treated with hypervolemic crystalloid resuscitation

et al. 2019

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“…The definitive treatment includes achieving hemostasis and blood transfusion. Packed red blood cells (pRBC) will be needed, along with platelets and fresh frozen plasma to restore the blood loss 56 . In shock associated with acute-on-chronic anemia, crystalloid or colloid boluses can also be harmful and blood resuscitation is needed.…”

Section: Treatment Of Shockmentioning

confidence: 99%

Advances in Monitoring and Management of Shock

Mtaweh

Trakas

et al. 2013

Pediatric Clinics of North America

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Synopsis Shock continues to be the proximate cause of death for many childhood diseases and imposes a significant burden. Early recognition and treatment of pediatric shock, regardless of etiology, decreases mortality and improves outcome. In addition to the conventional parameters (e.g., heart rate (HR), systolic blood pressure (SBP), urine output (UOP), and central venous pressure (CVP)), biomarkers and non-invasive methods of measuring cardiac output are now available to monitor and treat shock. In this article, we emphasize how fluid resuscitation is the cornerstone of shock resuscitation although the choice and amount of fluid may vary based on the etiology of shock. Other emerging treatments for shock i.e., temperature control, extracorporeal membrane oxygenation (ECMO)/Ventricular Assist Devices (VAD) are also discussed briefly in this article.

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“…HES is derived from amylopectin and produced by replacing glucose residue anhydroxyethyl with hydroxy-ethyl group at position C2 and C6. This makes the substitution of HES are more stable to amylase hydrolysis in the blood, thereby extending their shelf life (Spaniol et al 2007, Myburgh & Mythen 2013. These compounds can increase the circulating volume rapidly through increased oncotic pressure without causing tissue edema that often arise in the administration of crystalloid fluids (Macintyre et al 1985, Morisaki et al 1994, Moggio et al 1983, Munsch et al 1988.…”

Section: Introductionmentioning

confidence: 99%